578 



EFFECT OF COCAINE ON GROWTH OF LUPINUS 



An examination of Table III reveals the fact that the toxic dose of 

 benzoyl ecgonine is larger than that of ecgonine itself; in other words 

 the benzoyl ecgonine is less toxic than ecgonine. In order to inhibit 

 growth completely, concentrations of 0.1 molar, or 3.29 per cent, were 

 required. A concentration of 0. 1 molar, and lower ones, did not retard 



TABLE m. 

 Relation between Concentration of Benzoyl Ecgonine and Growth of Lupine Roots. 



TABLE IV. 

 Relation between Concentration of Methyl Alcohol and Growth of Lupine Roots. 



growth at all. It is evident that benzoyl ecgonine, unlike ecgonine 

 itself, is somewhat less toxic than cocaine. 



Rffect of Methyl Alcohol. — The results obtained with methyl alcohol 

 are shown in Table IV. This drug was found to be but Httle toxic 

 for lupine roots. It required a concentration of 1.5 molar, or 4.8 



