THE SPIROCH.ETE OF EGYFTIAX RELAPSING FEVEE 



69 



II. Monkeys (Cercopithecus sahaeus) 



Monkey No. 1, as already noted, was inoculated with some of the lieart's blood of gerbil 3, 

 at a time, however, when the latter animal exhibited no spirochsetes in its circulation. 



This inoculation proved negative, and, as an opportunity was afforded on January 25 of Successful 

 inoculating this same monkey (the only one which, on that date, could be obtained) with ^"^°'="^'°" 

 blood from one of the cases in hospital, this was done and the monkey received 

 subcutaneously three drops of finger blood from an Egyptian soldier who had relapsed 

 and was showing spirochsetes in his blood. The monkey was found to be infected on 

 January 29, there being a good many spirochsetes present in the peripheral circulation. 

 The incubation period was, therefore, apparently four days. This infection increased, and 

 by .January 31 might be described as heavy. On this day the animal looked somewhat 



lil'j S t.h ^ No 1 

 Cercopit/ucits iabaciis, i Disease: Relapsini; Fever (Egyptian) 



UAY 1 -1 3 4 5 6 7 8 9 10 11 12 13 14 16 16 17 18 19 20 21 22 23 24 2o 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 



D.^TE 25 26 27 28 29 30 31 1 2 3 4 6 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 1 2 3 4 5 6 7 



Fig. -(S. — + s;c;a=:6iiirt;chaetcs m lienjilienii cuvtiiatiou 



ill. No coryza was noticed. Its temperature was taken daily, and the chart (Fig. 26) 

 shows the course followed. On February 1, though the animal still appeared ill, no 

 spirochsetes could be found. On February 2 the monkey looked better and the search 

 was again negative. 



With the fear that one had delayed over long, a small quantity of finger blood was 

 taken, citrated and inoculated into monkey 2. 



Monkey 1 remained well and did not relapse. Although on February 13 its temperature 

 rose suddenly, no spirochsetes were found in its blood. 



At the time they were present, lice and ticks were fed on the monkey in connection Feedini,' 

 with experimental work on the possible carrier of the virus {cide page 71). e.\penmeinh 



Motikey No. 2 {Gercopithecus sahaeus). — Inoculated subcutaneously on February 2, from 

 monkey 1, at a time when the latter's temperature was still elevated, although spirochsetes 

 had apparently disappeared from its peripheral blood. It is unfortunate that a monkey was 

 not obtainable at an earlier period for inoculation with blood rich in spirochsetes, as no 

 infection occurred, but, as will be considered later, this negative result is of some interest 

 and importance. One cannot but regret that great press of work prevented these 

 inoculation experiments being carried out in a more extensive and thorough manner, 

 although it is true that the peculiar behaviour of the strain was one cause of the 

 limiting of the observations. It was only the importance of trying to come to a 



