206 TWO CASKS OK NON-ULCEKATING " OKIENTAI. SOKE" 



1)0 full('<l tlieir iiuck'i, stain a vt-iy rifh nihy-ri'd by tlio Kniiiaiiowsky method, and their 

 {general appcaranee is shown in V\<>s. 47 and 48. 



In none of thcin is there any appearance of a rod-sliaped Ijlepharophist, thou>;h some of 

 the longer forms show, in addition to the nucleus (?), red chromatin granules rather like 

 those met with in fusiform bacilli. Their cytoplasm stains a deep blue and in the long 

 forms is distinctly granular. They are all extra-cellular and occur singly or in little 

 groups. It is significant that no true Leishmania were present in the films. Perhaps 

 these bodies scarcely merit attention, but it seems worth while mentioning their presence 

 as it is difficult to place them and they might confuse otlier observers. On the whole 

 I think they are some kind of yeast or fungus, but I did not make any attempt to cultivate 

 them from the blood obtained by puncture of the growth. 



As will be seen this research has had to be left incomplete, but it is hoped that in 

 the future more cases of this peculiar condition may be seen, and that it may be possible 

 to cultivate the causative organism, to carry out the necessary animal inoculations and 

 to determine, no easy matter, the method of infection and transmission in man. 



Meanwhile, the reader is referred to Captain Archibald's account of an allied 

 cutaneous Leishmaniosis which it was possible to study in greater detail and which 

 presents several points of interest {vide page 207). 



