94 Vererbung-, Variation, Mutation. 



described a dwarf mutation of the Guinea-pig, which behaved as a Mendelian 

 recessive to the normal, and appeared chiefly in males. The present paper gives 

 data of all the families in which dwarfs have appeared up to the present time. 

 The ratio of normals to dwarfs in the total is exactly 3 : 1 (normal 192, dwarf 64). 

 In some families the dwarfs are all males, in others of both sexes, in others again 

 all females. In six families containing dwarfs of both sexes, there was a total 

 of 50 $ : 49 cf, of which 11 $ and 17 d" were dwarf. In seven families in which 

 all the dwarfs were male there w r as a total of 17 § : 54 d\ of which 21 were 

 dwarf males. In seven families in which the dwarfs produced up to the present 

 time are all female, the total is 24 $, 13d* and 4 sex not recorded; the females 

 include 13 dwarfs. Doncaster. 



235) Little, C. C, "Dominant" and "recessive" Spotting in Mice. In: 

 Amer. Natural., Bd. 48, Heft 2, S. 74—82, 1914. 



Though the hooded pattern in rats behaves as a simple Mendelian recessive 

 to seif colour, giving a 1 : 3 ratio, yet in mice the facts are not so simple. A 

 wild mouse was caught which had a spot or "blaze" in its forehead. This ani- 

 mal, which was a male, was crossed with a pure dilute brown female. The 8 off- 

 spring were all self-coioured and without a white spot. These F x animals bred 

 inter se produced (l) self-coloured (24), (2) individuals with white on their 

 coats. The latter were of two kinds, (a) those with only a few white hairs (17), 

 and (b) those with a "blaze" (ll). The animals with few white hairs, bred to- 

 gether produced again the three types. But the F 2 "blaze" animals, which 

 should behave as recessives, gave 4 self-coloured in a total offspring of 434. 



The writer concludes that shifting dominance and not a "dominant factor" 

 for Spotting is the cause of the variations in Spotting of mice. The results of 

 Durham and Hagedoorn are discussed, and the latter's conclusion that there 

 is repulsion between the color factor and the agouti factor, is considered in- 

 correct, since it appears that in certain cases there is failure to segregate and 

 complete disappearance of the dominant factor for agouti. Gates. 



236) Drinkwater, H., Minor-Brachydactyly. Nr. 2. In: Journ. of Genetics, 

 Bd. 3, Nr. 3, S. 217—220, 3 PI., 1914. 



Describes, with pedigree, a family showing minor -brachydactyly exactly 

 similar the case described by the author in Journ. of Genetics, vol. 2, 1912. The 

 middle phalanges are much shortened, but not ankylosed with the terminal pha- 

 langes. The condition is a simple dominant, transmitted only by the affected. 

 No relationship with the previously described family could be traced. 



Doncaster. 



237) Noby, Zur Casuistik und Therapie der angeborenen seitlichen Hals- 

 fistel. In: Deutsche Zeitschr. f. Chir., Bd. 126, Heft 3— 4, S. 348—356, 1914. 



Die beiden Fälle waren nach mehrfacher Richtung bin bemerkenswert. In dem einen 

 Falle hatten Mutter und Sohn dieselbe vollkommene Halsfistel. Dies ist wohl der erste 

 Fall, wo von einer Erblichkeit berichtet werden kann. Fernerhin bestand in deu beiden 

 Fällen des Verf.s geistige Minderwertigkeit. Sollte man die angeborenen Halsfisteln nicht 

 mit einreihen können in das Register der körperlichen Degenerationserscheiuungen, wie 

 deren die Psychiatrie so manche in engem Zusammenhang mit den Psychopathen bringt? 



Wagner. 



238) Tkorbecke, W., Über das familiäre Auftreten von Darmpolypen. 

 In: Deutsche Zeitschr. f. Chir., Bd. 126, Heft 5/6, S. 553—578, 1914. 



Im Anschluß an die Arbeiten von Verse und Döring hat Verf. die Tabelle 

 über die Fälle von Darmpolyposis fortgeführt und 23 weitere Beobachtungen 





