266 AiiniiaL Report for 1914 of Royal Veterinary College. 



the course of a fortnight. Treatment was begun with sulphate 

 of iron alone on June 17, and continued until July 25, 

 after which the diarrhoea ceased and the general condition 

 began to improve. It is a remarkable fact that during this 

 latter treatment visible shreds of mucous membrane were 

 passed with the fteces, and on microscopic examination these 

 were found to contain large numbers of Johne bacilli. 



Since July last the improvement in condition has been 

 steadily maintained, as is evidenced by the following figures : — 



4 lb. 



9 „ 



7 „ 



3 ., 



3 „ 



10 „ 



10 „ 



10 „ 



3 „ 



4 „ 



Fig. 3 shows the appearance of the cow at the time of 

 writing (November 20). 



Case III. — This was a Jersey cow, 3 years old, suspected to 

 be affected with Johne's disease in consequence of diarrhoea 

 and rapid loss of condition after calving. The diagnosis was 

 confirmed by rectal examination, and treatment with iron and 

 sulphuric acid was begun on December 10, 1913. On November 

 27 the animal's weight was 44 st, 4 lb., and by this time the 

 faeces were very loose and on occasion almost watery. The 

 treatment was stopped on December 19, and it was found that 

 on December 20 the weight was 46 st. 8 lb., representing a gain 

 of 2 St. 4 lb. 



During the next three weeks the condition of the animal 

 improved, and by the middle of January the diarrhsea had 

 quite disappeared. The improvement continued, and on March 

 14 the weight was found to be 50 st. 4 lb. About a fortnight 

 later, however, diarrhea again set in, and this was treated by 

 the administration of siilphate of iron without acid. After a 

 few weeks there was marked improvement, and the treatment 

 was discontinued. On June 6 the weight was 51st. 9 lb. The 

 condition of the animal at this time can be judged from the 

 accompanying photograph (Fig. 4), which was taken on 

 June 10. 



On June 20 the weight had increased to 52 st. 8 lb. About 

 July 9 the appetite began to fail, there was occasional diarrhcjea, 

 and on July 31 treatment with sulphate of iron alone was again 

 started] and contined for six weeks. In spite of that the cow 



