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injected ; intense headache ; slight epigastralgia ; pains in the spine ; tongue 

 coated ; no vomiting or other remarkahle symptoms. Treatment : 

 Ipecacuanha, four grammes in four doses ; cream of tartar lemonade ; 

 absolute diet. Evening: Temp. 100.4° F., pulse 88; resp. 26; headache less 

 intense. Night : Intense thirst ; urine scanty. 



3d day. Morning. — Temp. 99.6° F. ; pulse 72-resp. 34 ; skin pale ; 

 slight yellowness of conjunctivae; congested gums; epigastralgia; no 

 nausea ; no albumen in the urine. Evening : Albumen detected in the urine. 

 Night : Same condition ; insomnia. Treatment : One grame of sulphate of 

 quinine in ten doses ; cream of tartar lemonade ; mustard plasters to the 

 extremities. 



4th day. Morning: Temp. 98.9° F. ; pulse 72; resp. 34; no headache; 

 some appetite ; gums give a little blood on compression ; urine treated 

 by heat and nitric acid, gives a more abundant precipitate of albumen- 

 Evening : Normal temperature and pulse. 



5th day. Temp. 98.9° F. ; pulse 78; respiration normal; slight 

 jaundice; urine contains albumen. 



6th day. Convalescent; urine not examined; broth allowed. 



7th day. Continues well. 



12th day. Cured. 



The distinct evidence of . albumen in the urine, notwitstanding the 

 mildness of the fever and general symptoms, leaves no doubt regarding 

 the diagnosis, which was unhesitatingly reported as "regular yellow 

 fever. ' ' 



CASE II. — Another soldier of the group (A. L. C), seventeen years 

 of age, three months in Havana, was stung on the 22d of July, 1881, by 

 a mosquito which had bitten, on the 16th, a bad case of yellow fever (in 

 fifth day of his illness), and on the 20th had been made to sting my own 

 hand. 



July 27. Five days after the inoculation, this soldier entered the 

 Military Hospital with an attack of fever, which was qualified as "abortive 

 yellow fever." When seen by me on the 31st (fifth day of his illness), 

 there was scarcely any fever, and the urine contained no albumen. I was 

 unable to procure the clinical notes of this case. 



This observation would tend to prove that an infected mosquito does 

 not always lose its virulence by an intermediate bite. This is not always 

 the case, however, for on a subsequent occasion, having inoculated with a 

 mosquito which had bitten two yellow fever patients, a person who seems 

 thereby to have acquired subsequent immunity, the same insect was 

 afterward made to sting a second non-acclimated person, who had a 

 severe attack of yellow fever six months later, from which he fortunately 

 recovered. This case has not been included among my regular inoculations, 

 being considered a distinct experiment. 



