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in number, and all of them during the winter season. The influence of the 

 season is being just now exemplified by the greater virulence of the 

 attacks produced by inoculations which, in winter, under similar circums- 

 tances, would probably have been attended with mild results. Two unex- 

 pectedly severe cases, which ended fatally with black vomit, have thus 

 occurred at the Experimental Station, and furnish a warning not to place 

 too much reliance upon previous results obtained in a different season. 

 and evidently justify my former reluctance to experiment, on my sole 

 responsibility, with mosquitos, whose contamination had been allowed to 

 reach its fullest development. 



There are yet many important points to be accurately determined 

 before any one of us can consider himself in a position to discredit the 

 others' work. 



Charles Finlay, M. D. 

 Havana, August 20, 1901. 



