22 MALARIA 



corpuscles are distinctly enlarged and are quite pale. 

 There are no crescents in this species, and the gametes 

 are not easily distinguishable from the asexual parasites. 

 The number of elements in the sporulating or segmen- 

 tation stage (Fig. 2, c) is larger than in the former, and 

 their arrangement is irregular (fifteen or more, accord- 

 ing to Stephens and Christophers). 



c. Laverania malarice {Plasmodium malarice, Hcema- 

 mceba malarice) is the cause of quartan fever, with 

 recurrent paroxysms every seventy-two hours. This 

 form of malaria is comparatively rare, and coincides 

 in distribution with sestivo-autumnal fever. In the 

 parasites the pigment is coarse and generally occurs in 

 a streak along the margin (Fig. 2, b"). The parasitized 

 corpuscles are commonly shrunken and may appear 

 as "brassy bodies." The gametes are rarely seen. 

 The segmenting stage gives rise to the typical "daisy" 

 form, each sporulated body radiating from the center 

 (Fig. 2, c"). The number of bodies varies from six 

 to twelve, oftenest eight (Deaderick). 



The signet ring (Fig. 3) is a young stage in the de- 

 velopment of the intracorpuscular parasite of all species, 

 and is characterized by a broken ring, whose ends are 

 connected more or less loosely by a chromatin dot, 

 which in the sestivo-autumnal parasite may be double. 

 The chromatin dot is often inside the ring, but ordi- 

 narily nearest the thin segment of the ring. 



Life History of the Parasite. — Only one phase of 

 the life history (the asexual), or cycle of Golgi (repeated 



