oj± SKIN DISEASES TREATED BY BLOOD VACCINE. 



and bacilli were visible in the blood plasma, and some 

 of the cells also seemed to contain cocci. An acne vaccine 

 was made from the blood drawn through an acne nodule. 

 The skin of the forehead was thoroughly scrubbed 

 with ether soap and absolute alcohol, and then collodion 

 was painted over the spot to be pricked, and the blood 

 taken from the surface of collodion as it welled through. 

 The skin was so thoroughly treated that it peeled off the 

 forehead for the next week or so. 



A culture of the blood gave numerous cocci and some 

 bacilli, which formed small, gaseous bubbles in the neu- 

 trient agar. Injection with a vaccine made from this 

 when given too freely on one occasion brought on a 

 severe attack of nausea and shivering, with frontal head- 

 ache and great lassitude — "one of my old attacks," the girl 

 called it. The acne disappeared entirely, and the blood 

 showed a most gratifying picture — the hi\\h was perfectly 

 clear, with none but multinuclear leucocytes present, and 

 the platelets somewhat in excess, due to breaking down 

 of exuberant leucocytes. 



Lichen Acuminatis in at least two patients has re- 

 sponded to similar treatment. In these cases a vaccine 

 prepared from the bloQd was used. One patient showed 

 symptoms of general anaemia, with oedema of lower 

 limbs, constant pain in left hypochondriac region. The 

 skin, after several injections of vaccine, is peeling off, 

 leaving a smooth, epithelial surface, while the general 

 condition is vastly improved. 



Another set of skin affections, apparently having their 

 origin in general blood infection, is the herpetic which 

 occurs as a chronic condition by no means rarely. A 

 culture of blood in such a case within the past month 

 has given me a pure cultivation of a bacillus, probably 

 the colon. And this is what one would expect to develop 

 in such a condition where the skin lesion is caused by a 

 localised peripheral neuritis. It has proved very obstin- 

 ate to ordinary remedies, and has disappeared rapidly 

 after treatment with an autogenous blood vaccine. 



Pemphigus is now considered a streptococcal infection, 

 and it also should be treated by a vaccine made either 

 from a fluid in the vesicle or from the blood of a patient. 



