vague. We must not stop our work until the Tollowing have been accomplished: 



1. Investigation of the spawning seasons of poisonous fishes 



2» Investigation of the food of poisonous fishes 



3. Animal feeding teots with each of the organs of raw poisonous fishes 



4„ Tests on experimental animals with poison from the various organs of 



poisonous fishes without using cheraical techniques 

 5. Serological studies of poisonous fishes 



Such studies should reveal where the toxic element is located and its 

 relation to the gonads and to the food habits of the fish. Once this has been 

 accomplished, if the toxin is sought bv chemlcp.l techniques, it will be pos- 

 sible to clarify its pharmacological significance and it vdll not be difficult 

 to find its clinical applications. 



The essential point Is that the work should be done in the field with 

 fresh material to ascertain the presence of poison by means of experiments on 

 animal So 



These investigations are truly difficult and they will not, of course, 

 be accomplished in a day, but on the other hand I believe that they are im- 

 portant problems which should be clarified. 



197 



