1902.] NATURAL SCIENCES OF PHILADELPHIA. 319 



iu fig-s. 8 aud 9, Plate XVI, and iu many other cells of the same 

 iutestiue, measure from .5,u to 2,u; they were precipitated with picro- 

 acetic.'' The granules iu fig. 12 and several other cells of the 

 game intestine measure from .5,a to 1.5//; they were precipitated 

 with Hermann's fluid. It is not important to attempt an exact 

 determination of the strength in wliich the albumose may exist in 

 the cells ; but the above figures indicate that it may be as strong as 

 a 10 per cent, solution, making allowance for the fact that Fischer's 

 measurements were made for pure solutions, whereas iu the cells 

 they are of course mixed with other interalveolar substances. 

 Fischer notes that albumose in mixture with an albumen pi'ecipi- 

 tates larger granules than from pure solutions. He also observes 

 that precipitated from such mixtures they are not uniformly dis- 

 tributed through the coagulum of the albumen, but are collected 

 into small and large nests (" Anhaufung in Nestern "). Figs. 8 

 and 9, Plate XVI, and others show this arrangement. 



^ B 



Fig. 13. — Granules of Peptone (depur. sice, aus Fibrine), (Giiibler) X 

 925. A, 2.5 per cent. ; B, 5 per cent, solution precipitated on cover-glasses 

 by Chromic acid (1 per cent.), stained in Irou-Htematoxylin. See Table 

 II, Nos. (5) and (6). 



The occurrence of little spaces about each granule of albumose 

 in a coagulum of albumen, which Fischer has figured (/. c. Taf., 

 figs. 2, 3,- 4), is confirmed also by my figs. 6, 8 aud 9, Plate XVI. 

 This fact enables one to determine with clearness the relation of the 

 granule to the alveolar structure of the cytoplasm. Thus, if the 

 granule were precipitated within the alveole, and the structure were 



^' Picroacetic is said by Fischer to precipitate albumose iu a soluble 

 form. I find this to be true if the fixation is followed by washing with 

 water, but if followed with 70 per cent, alcohol the granules are not 

 dissolved m this or subsequent fluids. The same is true of picro-sul- 

 phuric. 





