72 



Malaria patients were treated mainly in isolation camps. No fatal 

 case was recorded during the whole summer. It is very desirable that 

 special laboratories under the control of the anti-malarial mission 

 should be established wherever possible near the military stations. 



Cot ( — ) & HovASSE ( — ). Quelques Remarques sur les Anoph61ines 

 de Mac6doine. [Some Remarks on the Anophelines of Macedonia.] 

 — Bull. Soc. Path. Exot., Paris, x, no. 10, 12th December 1917, 

 pp. 890-896. 



In the course of a study of the Anophelines of Macedonia, the 

 authors have found only three species in the region of Salonika, namely, 

 Anopheles maculipennis, A. bifurcatus and a variety of A. {Pyretophorus) 

 superpictus for which the name macedoniensis is proposed. A. bifurcatus 

 is extremely rare and none of the specimens captured proved to be 

 infected. A. maculipennis abounds mainly in marshy land, and with 

 it colonies of A. macedoniensis occur, both species being vectors 

 of malaria. The latter form is described and differentiated from 

 its allies, A. superpictus and A. palestinensis. The hfe-cycle of 

 these Anophelines is essentially variable, particularly in the larval 

 stage, the duration of the larval development being dependent upon 

 temperature and nutrition. It was found, contrary to the generally 

 accepted opinion, that neither an altitude of about 3,000 feet, nor a 

 night temperature as low as 50° F. , is sufficient to arrest development 

 The minimum period of development has been recorded in mid- August, 

 nymphs of A. superpictus var. macedoniensis having been obtained in 

 36 hours under natural conditions. This period, which is shorter than 

 anything previously recorded, indicates the probability of an additional 

 generation of Anophelines in Macedonia during the summer season. 

 Though Hydrachnid larvae have been recorded as ecto-parasites of 

 Anophehne larvae and though many were present in the streams 

 examined, no such parasitisation was observed. A considerable 

 number of larvae were found parasitised by microscopic algae, and 

 their development was considerably retarded in consequence. These 

 individuals however produced normal nymphs some 20 days later than 

 unparasitised ones, and it is evident that the internal changes prepara- 

 tory to the nymphal stage entirely eliminated the parasite. This fact 

 has apparently not been previously recorded, and is of importance as 

 having a bearing on the malaria question, since these parasitised 

 larvae, developing after varying periods, produce, as it were, a 

 continuity of hatching between the successive generations. 



The percentage of Anophelines found to be infected was 8 per cent., 

 the ookinetes apparently agreeing with the characteristics previously 

 described for Plas7nodium falciparum. Oocysts were found in various 

 stages of evolution. Only in three cases were the salivary glands found 

 to be infected. It is the authors' intention to discuss this subject 

 further when investigations have been completed. 



SuLDEY (E. W.). L'Index end6mique du Paludisme ^ Madagascar. 



[The Endemic Index of Malaria in Madagascar.] — Bull. Soc. Path. 

 Exot, Paris, x, no. 10, 12th December 1917, pp. 915-923. 

 This paper gives the results of many blood-examinations of native 

 children in Madagascar during a journey on the west coast in 1913-1914^ 



