140 



1911-1912. Three individuals of Culex pipiens had a meal of blood 

 heavily infested with Plasmodium relictmn on 6th October 1911. 

 Numerous observations have shown that in such conditions the 

 mosquito always becomes infected. These three individuals were 

 kept in the laboratory nearly 5 months without a blood meal. After 

 that interval, two of them were allowed to bite a healthy canary, 

 without producing any infection. An examination of the salivary 

 glands of the third individual 10 days later showed numerous appar- 

 ently normal sporozoits. A fortnight later (the maximum duration 

 of the incubation period), the bird received an experimental injection 

 which caused, after the usual interval, a strong infection of the Plas- 

 modium that proved fatal on the 11th day. It is therefore concluded 

 that, under certain conditions, Plasmodium relictum cannot preserve 

 its virulence in the mosquito after several months of hibernation ; 

 neither did an inoculation of the degenerated Plasmodium confer 

 immunitv on the bird. 



Caille (E.). Cas de Paludisme autochtone rennais k Plasmodium 

 falciparum d6cele par une Injection de N6osalvarsan. [A Case of 

 indigenous Malaria at Rennes due to Plasmodium falciparum 

 revealed by an Injection of Neosalvarsan.] — Btdl. Soc. Path. 

 Exot., Paris, xi, no. 4, 10th April 1918, pp. 282-286. 



A case is recorded of a woman who had never left the town of 

 Rennes being infected with Plasmodiitm falciparum. This infection 

 became evident only after an injection with neosalvarsan, and the 

 irregular fever thus produced yielded to quinine treatment. 



Rousseau (L.). Recherches sur I'End^mie palud6enne a Doua'a 

 (Cameroun) en 1917. [Investigations into endemic Malaria at 

 Duala (Kamerun) in 1917.] — Bull. Soc. Path. Exot., Paris, xi, 

 no. 4, 10th April 1918, pp. 286-291. 



Investigations carried out at Duala from January to March, 1917, 

 confirms the opinion that malaria in this district is inevitable among 

 newly-born infants, who from their birth must receive infection 

 again and again under the normal conditions of native life. The 

 results are given of examinations of natives of various ages in 

 different districts. While making these examinations, the breeding- 

 places of Anophehnes were diligently sought for. These are difficult 

 to trace during the dry season, but as soon as the rains begin they may 

 be found abundantly. Very few occur among vegetation ; the majority 

 are on the roads and in the yards of houses, almost all being close to 

 inhabited places. Evidently the species in question is maintained 

 during the dry season by breeding in the rare permanent breeding- 

 sites, or by females that are able to live from one rainy season to 

 another, and a dangerous increase in numbers occurs as soon as the 

 rains begin and suitable collections of water are to be found. A 

 long drought would be necessary to dry up the marshy land sufficiently 

 to suppress the danger ; unfortunately rain is so frequent that the 

 ground becomes saturated and is often coated with elementary algae, 

 thus constituting a permanent breeding-ground that can defy several 



