70 



Appendix A. 



(Reduced from original) 



Recent observations Ln the intensely malarious districts of Italy and Africa 

 have shown, that even newcomers in these regions, who purposely expose 

 themselves by living in the most highly malarious areas (for example, the 

 Roman Campagna), do not develop malarial fever, if they are carefully pro- 

 tected from the bites of mosquitoes; and further it has been shown that this 

 disease may be produced with certainty if an Anopheles mosquito is allowed 

 to bite a person suffering from malarial fever, and then after a sufficient 

 time elapses, is allowed to bite a healthy person. 



frs 



Tig. 1. — Larva of Cules. 



