338 E. ROBERTS AND D. G. SIMONSEN 
within 24h after restoration of potassium. In the kidney potassium deficiency re- 
sulted only in increases in lysine and arginine, and no changes were noted in the 
liver. However, no changes in any of the detectable constituents were found in 
extracts of skeletal muscle, left ventricle and kidney of severely potassium-deficient 
dogs®. 
The above studies show that although some compensatory changes may occur in 
the free amino acid of some tissues of some species when disturbances are induced 
in the distributions of the major electrolytes, these changes are not obligatory. The 
above results emphasize further the stability of the mechanisms which are conserv- 
ative of the characteristic steady-state concentrations of the free or easily extract- 
able amino acids. 
Vitamin A deficiency. A recent study of amino acid patterns in tissues of vitamin 
297. 298 

% oa 299 

Pigs. 297-302. Effect of dehydiation and inanition on free amino acids of muscle (75 mg). Fig. 297: 
control. Figs. 298, 300, 302: dehydrated for 24, 48 and 68 h, respectively. Figs. 299, 301: starved 
for 24 and 48h, respectively. Serine, to; glutamine, 13; glycine, 14; Br, brown spot of carnosine 
and anserine. 
References p. 348/349 
