FREE AMINO ACIDS IN ANIMAL TISSUE 341 
Diabetes and hypoglycemia. Six Long-Evans rats approx. 200g in weight were 
fasted for 48h and then injected intravenously with 40 mg/kg of alloxan. All the 
treated animals exhibited a glycosuria and elevated blood-sugar levels. The diabetic 
animals and the littermate controls were sacrificed 1 month after the injection and 
the easily extractable ninhydrin-reactive constituents were determined. The patterns 
found in the diabetic animals were virtually identical with those found in the con- 
trols, the differences between the patterns in normal and diabetic littermates being 
no greater than those observed from one normal animal to another. Typical results 
307 308 
310 
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ro 

Sd 312 

= 
Figs. 307-312. Amino acids of extracts from 75 mg samples of brain (Fig. 307), muscle (Fig. 309) 
and kidney (Fig. 311) of normal rats and brain (Fig. 308), muscle (Fig. 310) and kidney (Fig. 312) 
of diabetic littermates. Carnosine and anserine, 26. 
References p. 348/349 
