344 E. ROBERTS AND D. G. SIMONSEN 
suitably paired young adult Sprague-Dawley rats was employed to induce the 
hyperthyroid state. Typical results in Figs. 321-326 show that no changes, what- 
soever, had taken place in the amino acid distribution in liver, muscle, or kidney. 
Experiments were then performed with Sprague-Dawley rats that were surgically 
thyroidectomized at 40 days of age and were sacrificed together with lttermate 
controls at 5, 9, 17, 24, 29, 38 and 45 days, respectively, after surgery. Extracts of 
brain, liver, kidney and muscle were chromatographed in the usual fashion. The 
only consistently reproducible difference found between the experimental and control 
groups was an increase in the content of ethanolamine phosphate in the extracts of 
the kidneys of the thyroidectomized animals. An impression was also gained that the 
taurine level was elevated in liver of the thyroidectomized rats. 
321 322 

326 

5-mg samples) of muscle 
326. Failure of thyroxin injection to affect free amino acids (75 
‘ig. 324: thyroxin), or liver 
I 321 | 
(Fig. 321: control. Fig. 322: thyroxin), kidney. (Fig. 323: control. Fi 
(Fig. 325: control. Fig. 326: thyroxin). 
References p. 348/349 
