398 G. ROUSER et al. 
133 

134 137 
138 
a ely 

Figs. 133-138. From a patient with chronic lymphatic leukemia before and after treatment with 
nitrogen mustard. Aliquots equivalent to 0.25 ml of plasma and erythrocytes, and extracts of 
roo mg of leukocytes. Figs 133-135 plasma, erythrocytes, and leukocytes before treatment; 
Figs. 136-138, 2 days after injection of nitrogen mustard. 
taurine in erythrocytes after the drug was administered. Fig. 141 shows that the 
leukocyte free amino acid pool was similar to the previous sample except that 
glutathione was greatly reduced in leukocytes after the total dose had been ad- 
ministered. 
Figs. 142-144 show plasma, erythrocytes and leukocytes 21 days after the ad- 
ministration of the total dose of nitrogen mustard. The plasma sample (Fig. 142) 
shows profound changes. The taurine level was low and the glutamic acid level was 
References p. 447/448 
