FREE AMINO ACIDS IN BLOOD. IV 399 
139 142 
# a A 
", 
. FF KY 
~ GA 
eee 
Gl 
140 143, 
' / 
Ne 
141 ae | 144 

‘igs. - , 5 days from start of nitroge1 ustard administration; Figs. 2 , 21 days 
Figs. 139-141, 5 days from start of nitrogen mustard administration; | 142-144, 21 day 
after nitrogen mustard. Note the changes in glutamine, glutamic acid, and glutathione (arrows). 
For abbreviations see p. 369. 
below that seen in the control plasma sample. The most marked change was the 
almost complete absence of glutamine in plasma. The erythrocyte sample (Fig. 143) 
shows the return of glutathione to the red cell pool and a very low total free amino 
acid content. The most marked change in the leukocyte pattern was the complete 
disappearance of glutathione from these cells. Another blood sample (not illustrated) 
was examined 40 days later (61 days after the complete dose of nitrogen mustard 
had been given) and the free amino acid levels had returned to approximately the 
pretreatment state. 
Before administration of nitrogen mustard, the patient’s peripheral leukocyte 
References p. 447/448 
