FREE AMINO ACIDS IN BLOOD. V 423 
232 

2 DAYS 235 

| ue 

“ a 
Figs. 232-237. Extracts of 50 mg of leukocytes from M. Fal. after 5 mg of dimethylmyleran. 
Note the marked fall of all free amino acids in the 2 day sample. For abbreviations see p. 369. 
above the control level, while the cysteic acid and cysteinylglycine spots were 
markedly decreased. 
The plasma glutamic and aspartic acid levels were greatly reduced after 20 mg 
of drug. It is of considerable interest that this change is in the reverse direction to 
the trend in the untreated patients (the level of glutamic acid is frequently increased 
above normal). Figs. 247-249 illustrate the findings with the erythrocytes. The 
glutamine level of the control erythrocyte sample was exceptionally low. The fall in 
aspartic and glutamic acids seen in the plasma was observed in erythrocytes. The 
fall in the erythrocyte glutamic acid level was the most pronounced change. 
The findings with plasma at the high dosage level in this patient represent inter- 
mediate effects when compared to the findings in other patients. The leukocyte and 
erythrocyte responses, however, represent some of the most marked effects observed 
in any of the patients. 
References p. 447/448 
