428 G. ROUSER, K: KELLY, B. JELINEK, D. HELLER 


262) aE Sone 265 







263 266 
264 ea. “5 See 
% | 
ome} | 

Figs. 262-267. For legend see p. 426. 
plete characterization has not been possible. One of the unknowns, a substance 
moving to the left of glutamic acid on two-dimensional chromatograms (after oxida- 
tion with hydrogen peroxide), has the chromatographic characteristics of cysta- 
thionine. The unoxidized material moves in the ethanolamine-O-phosphate region. 
One of the changes produced by dimethylmyleran and myleran is in the reverse 
direction to the change observed in the untreated patient. The higher than normal 
glutamic acid level seen in the untreated patient, is reversed by the drugs. 
Dimethylmyleran produces a drop in both glutamic and aspartic acids that can be 
seen in plasma, erythrocytes, and leukocytes, 
References p. 447/448 
