440 G. ROUSER et al. 
glutaminase assays of erythrocyte glutamine levels show clearly the small increase 
of glutamine in red cells after amino acid ingestion. 
Two additional studies were carried out with subject H. Gol. after treatment with 
dimethylmyleran when the leukocyte count had been reduced to about 40%, of the 
pretreatment level. The findings in both studies (not illustrated) were much more 
similar to those obtained with normal individuals and the patient with chronic lym- 
phatic leukemia. 
The free amino acid levels of the blood platelets were examined by paper chro- 
matography in one study of patient H. Gol. after treatment with dimethylmyleran. 
Figs. 373-376 show the free amino acid levels of platelets in the control sample 
(Fig. 373) and 30, 60, and 240min after ingestion of glutamine (Figs. 374-376, 
respectively). The arrows in the figures point to the position of glutamine that can 
be seen to rise and fall. The study thus established that platelets can concentrate 
glutamine. The findings are similar to those obtained with leukocyte samples. 
PLASMA 
Mg GLUTAMINE / ml 

30 60 390 120 150 180 210 240 
TIME (min) 
PLASMA 
Mg GLUTAMINE / ml 

30 60 30 120 150 180 240 
TIME (min) 
Figs. 377 and 378. Glutamine levels (glutaminase assay) of plasma and cells after glutamine 
ingestion. Subjects Q. Tur. (Fig. 377) and R. Tap. (Fig. 378). 
References p. 447/448 
