788 
Deilephila euphorbiae, soluble proteins, 129 
Dendrostoma zostericolum, amino acids, 180, 181 
Deoxycorticosterone, effect on amino acid ac- 
cumulation, 577 
—, — — in rat tissues, 337 
—, — uptake in Neurospora crassa, 99 
Deproteinization, blood and urine, 22 
—, effect on plasma amino acids, 509 
Desalting, of blood plasma, 223 
Desmethylimipramine, effect on amino acids in 
brain, 465-467 
Destruction of amino acids, by peroxide, 355 
Development, changes in amino acid pool, 136, 
298-306 
—, effect on brain y-aminobutyric acid, 474 
—, — protein turnover, 683 
—, insect, effect on pool composition, 116, 118 
—, variation of brain glutamic acid and 
glutamine, 473 
Diabetes, blood amino acids content in human, 
207 
—, effect on amino acids in rat tissues, 341-343 
—, plasma amino acids in rat liver perfusion, 
715 
a, y-Diaminobutyric acid, uptake by Ehrlich 
ascites tumor cells, 322, 324, 325 
Diaminopimelic acid, in Corynebacterium diph- 
theriae, 80, 81 
—, in peptides, 89 
Diapause, pool changes, 124 
Diaphragm, rat, effect of potassium deficiency 
on amino acids, 337 
—, —, tyrosine pool heterogeneity, 770 
Diastereomatic mixtures, separation, 12 
Dicotyledonous plants, pool changes during 
seed germination, 657, 658 
Dictyostelium discoideum, age, effect on pool, 
95 
—, amino acids, 86 
Dieldrin, effect on brain amino acids, 515, 516 
Diencephalon, chicken brain, amino acids, 303, 
394, 
Diet(s), amino acid imbalance, 519-521, 524 
—, chemically defined, 513, 515 
—, effect on amino acids, in blood, 268—270 
— — EXCLELION, 220, 249.250.127.451 275 
—, —, in plasma, 238 
—, —, in rat tissues, 334-340 
—, galactosemia, 211 
—, maple-syrup urine disease, 214 
—, phenylketonuria, 213 
Diethylglutamate, uptake by Staphylococcus 
aureus, 573 . 
Differentiation, effect on protein synthesis and 
turnover, 684—686 
—, relation to pool composition, 95 
Diffusion, amino acids into yeast, 641 
—, exchange (see Exchange diffusion) 
Digestive diverticulum, abalone, amino acids, 
183 
Dihydrocortisone, effect on amino acid 
excretion, 229 
3, 4-Dihydroxyphenylalanine, 
fungi, 86 
occurrence in 
SUBJECT INDEX 
Dusopropylfluorophosphate, inhibition lipid— 
amino acid synthesis, 746 
Dimethylmyleran, effect on amino acids in 
blood fractions, 414-429 
—, use in treatment of leukemia, 413, 414 
Dimethyltaurine, occurrence in red algae, 168 
Dinitrobenzene, effect on urine amino acids, 277 
Dinitrofluorobenzene derivatives, of amino 
acids, 354 
Dinitrophenol, effect on pool, 99 
2, 4-Dinitrophenol, differential effect on entry 
and exit, 533 
—, effect on amino acid accumulation, 573, 574 
—, lipid—amino acid synthesis, 751 
—., tyrosine transport, 550 
—, inhibition of protein degradation, 651 
Diphenylhydantoin, effect on brain glutamic 
acid, 468 
Dipicolinic acid, occurrence in bacterial spores, 
81 
2,5-Di-n-propoxy-3,6-bis-ethylenimino- 
benzoquinone (see E-39) 
Diptera, amino acids, 117-119, 123 
Distribution ratio, amino acid, HeLa cells, 696, 
697 
Diurnal cycle, effect on pool composition, 669 
Dixippus morosus, amino acids, 120 
Djenkolic acid, occurrence in Tilletia caries, 86 
Dociostaurus maroccanus, peptidases in eggs of, 
125 
Dog, blood plasma, effect leukemia on amino 
acids, 379, 381 
—, brain, amino acids, 472, 474, 479 
—, —, effect ammonia intoxication on amino 
acids, 340 
—, —, ethanolamine derivatives, 481 
—, —, increase in glutamine after 
hepatectomy, 449 
—, erythrocytes, effect 
acids, 379, 381 
—, heart, amino acids, 287 
—, —, amino acids in, during myocardial in- 
farction, 306, 307, 309, 310 
—, leukocytes, effect leukemia on amino acids, 
379, 381 
—., liver, role in maintaining free amino acid 
levels, 449 
—, herve, y-aminobutyric acid, 474 
—, urine, amino acids, 201 
Donax variabilis, taurine, 165 
Dosidicus gigas, giant nerve axoplasm, amino 
acids, 473, 476, 478, 479 
Dosinia discus, taurine, 165 
Drosophila, incorporation of amino acids, 147— 
154 
—, larvae, injection of, 147 
—, lipid—amino acids, 747, 752 
Drosophila melanogaster, accumulation of trypto- 
phane, 129 
—, amino acids, 117, 118, 125 
—, changes in pool during development, 136 
— (egg), amino acids, 124 
—, essential amino acids, 127, 128 
—, peptides, 136 
leukemia on amino 
