792 
Glutamine, (continuation) 
—, effect ammonia on brain levels of, 340 
—, effect on plasma amino acids, in eviscerated 
Lat; 7LO ee 72k 
—, —, in liver perfusion, 715, 716, 718 
—, in Ephestia kiihniella, 116 
—, in human cerebrospinal fluid, 202 
—, importance in plant metabolism, 667 
—, ingestion, effect on amino acids in blood 
and urine, 430-447 
—, in insect hemolymph, 131 
—, inverse relation to asparagine, 671, 672 
—, liver and kidney, effect lymphosarcoma, 330 
—, low levels in myeloblasts, 377 
—, in mammalian cell metabolism, 695 
—, measurement, 5I1I 
—, metabolism, 447 
—, — by ascites tumor cells, 321-322 
—, — in brain, 340 
—, — carrot explants, 674, 675 
—, —, chronic lymphatic leukemia, 359-361 
—, —, importance in leukemia, 386 
—, — insects, 131 
—, — plants, 669 
—, mouse, liver, changes during development, 
299, 300 
—, In nerve, 473 
—, in plant tumors, 68 
—, in plasma, effect nitrogen mustard, 399 
—, — and tissues, effect adrenalectomy on, 
451-454 
—, — —, effect ammonium salts, 454, 455 
—, — —, effect evisceration, 451-454 
—, — —, effect glutamine, 454-456 
—, — —, effect insulin, 451-454 
—, — —, effect protein hydrolysate, 455, 456 
—, — —, effect temperature on, 451-454 
—, population-dependent growth requirement, 
7O1, 702 
—, in rat brain, 511 
—, reduced level in leukocytes in chronic 
lymphatic leukemia, 394 
—,—pplasma level in chronic granulocytic 
leukemia, 385 
—, requirement for poliovirus synthesis, 703 
—, role in protein synthesis, 689 
— synthesis, 672, 673 
—, — from glutamic acid, 724, 726, 727 
— synthetase, adaptive increase, 702 
— —, in microsomes, 725, 729 
— —, relation to glutamate transport, 591 
—, tissue levels, effect hepatectomy, 449, 450 
—, uptake by ascites tumor cells, 319-322 
—, — by carrot explants, 681 
—, variation in plasma, in chronic lymphatic 
leukemia, 388, 389 
—, in Walker carcinoma during autolysis, 295, 
296 
Glutamylalanine, in Escherichia coli, 89 
— y-aminobutyric acid, in Escherichia coli, 89 
y-Glutamylalanine, formation by transpepti- 
dation, 61 
—, in Pisum sativum, 56 
— f-alanine, occurrence in [vis tingitana, 55 

SUBJECT INDEX 
y-Glutamyl- (continuation ) 
— S-allyl-L-cysteine, in garlic, 63 
— B-aminoisobutyric acid, in Iris tingitana, 55 
— P-aminopropionitrile, occurrence in Lathyrus 
odoratus, 56 
— bond synthesis, 689 
y-L-Glutamyl-S-(/-carboxyl-N-propyl) 
cysteinylglycine, occurrence in Allium cepa, 
22) 
y-Glutamyl compounds, physiological role, 62, 
63 
— cysteine, in leukocytes, after triethylenemel- 
amine, 408 
— —, occurrence, 57 
— —, synthesis, 61 
—ethylamine, in Camellia sinensis, 56 
— —, in Xerocomus badius, 56 
— glycine, metabolism, 72 
N-(y-L-Glutamyl)-4-hydroxyaniline, occurrence 
in Agaricus hortensis, 57 
B-N-(y-L-Glutamy]l)-4-hydroxymethylphenyl- 
hydrazine (Agaritine), occurrence in A garicus 
bisporus, 44, 57 
y-L-Glutamyl-hypoglycin (hypoglycin B), 
occurrence in Blighia sapida, 56 
y-Glutamylisoleucine, occurrence 
cepa, 50 
— leucine, in Allium cepa, 63 
— —, in Phaseolus limensis, 55 
— methionine, in Allium cepa, 63 
——, in Phaseolus vulgaris, 56 
— methylcysteine, transport in plants, 63 
— S-methylcysteine, occurrence in Allium 
cepa, 03 
y-L-Glutamyl-S-methyl-L-cysteine, in Phaseo- 
lus limensis, 54 
— —, — Phaseolus vulgaris, 54 
— — sulfoxide, occurrence in Phaseolus limen- 
Sts, 54, 55 
y-Glutamyl 
tissues, 59 
— —, occurrence in plants, 54-63 
— —, role in protein synthesis, 72 
—  —, role in transport, 63 
— —, susceptibility to hydrolysis, 60 
— —, utilization by Lactobacillus avabinosus, 
60 
—.-phenylalanine, in Allium cepa, 55 
— —, in Glycine max, 55 
—.-tyrosine, occurrence in Glycine max, 55 
— valine, occurrence in Allium cepa, 56 
Glutathione, absence in myeloblasts, 377 
—, in blood cells, effect nitrogen mustard, 397, 
398 
—, brain, 472, 479, 480 
—, —, effect psychotropic drugs, 466, 468 
—, changes in heart during infarction, 310 
—, conversion to S-sulfonate, 224 
—, in dog heart, 292, 293 
—, in Ehrlich tumor, effect sarkomycin, 316 
—, in Escherichia coli, 83 
—, growth stimulation in Drosophila, 128 
—, in HeLa cells, 696 
—, in leukocytes, effect chlorambucil, 402, 403 
in Allium 
peptides, distribution in plant 
