796 
Internal pool, 102, 571, 575, 636, 638, 640, 706 
—, Ehrlich ascites cells, 615 
—, extraction, 655 
—, intracellular state, 655 
—, location in ribosomes, 655 
—, origin of amino acid, 641 
—, relation to protein synthesis, 656 
—, replenishment by protein degradation, 647 
—, retention on macromolecules, 641 
—, stability, 640 
=, WEES I 
Intestinal absorption, amino acids in insects, 122 
—— tract, sea urchin, amino acids, 184, 185 
Intestine, amino acid transport, 533-535 
—, cell culture, amino acid uptake, 698 
Intracellular state, amino acid pool, 290-292, 
702-777 
—, dipicolinic acid, 81 
Iodine metabolism, insects, 131 
Iodoacetate, effect on tyrosine transport, 550 
Iodohistidine, excretion by Peviplaneta ameri- 
cana, 131 
Ion accumulation, relation to protein synthesis, 
682, 683 
— -exchange chromatography, continuous 
counting of effluent, 259-261 
—  —, methods, 221-225 
Iproniazid, effect on amino acids in brain, 489, 
490 
Ivis tingitana, y-L-glutamyl-f-alanine, 55 
—, y-L-glutamyl-f-aminoisobutyric acid, 55 
Isethionic acid, squid giant nerve axoplasm, 476 
Isoleucine, excretion in maple-syrup urine dis- 
ease, 213, 255 
—, leucine, dietary balance, 519, 520 
—, separation from alloisoleucine, 12, 13, 51 
—, synthesis from aspartic acid, 643 
Tsonicotinic acid hydrazide, effect on pool 
composition, 97 
Isovaline, uptake, 529, 531 
Jejunum, chicken, serine ethanolamine phos- 
phodiester, 190 
Jerusalem artichoke (see Helianthus tubevosus) 
—, pool size, 676 
Kalanchoe daigremontiana, amino acids, 36-38 
Keto acids, effect ACTH on excretion of, 270 
—, role in nitrogen metabolism, 2 
a-Ketoisocaproic acid, excretion in maple-syrup 
urine disease, 214 
a-Ketoisovaleric acid, excretion in maple-syrup 
urine disease, 214 
a-Keto-f-methylvaleric acid, excretion in 
maple-syrup urine disease, 214 
Kidney bean seed (see Phaseolus vulgaris) 
—, chicken, serine ethanolamine phospho- 
diester, 190-192 
— damage, by cystine, 518 
—, human, effect on blood amino acids, 269 
—, —, — disorders on urine amino acids, 276 
—, —, Maturation, 273 
—, rabbit, effect nitrogen mustard on amino 
acids, 406, 407 
SUBJECT INDEX 
Kidney, (continuation ) 
—, rat, amino acids in animal with lympho- 
sarcoma, 330-331 
—, —, — during autolysis, 295, 297 
—, —, — diabetes, 341, 343 
—, —, — during starvation and dehydration, 
335, 330 
—,—, effect adrenalectomy and hypophys- 
ectomy on amino acids, 345, 346 
—, —, — aminooxyacetic acid on amino acids, 
595 
—, —, — hydroxylamine on amino acids, 504 
—, —, — potassium deficiency on amino acids, 
338 
—, —, — thyroxin and thyroidectomy on 
amino acids, 344, 345 
—, —, — vitamin A deficiency on amino acids, 
339, 340 
Krebs’ cycle, relation to amino acid pool, 516 
Kwashiorkor, 196, 269, 523 
Lactobacilli, amino acids, 77 
Lactobacillus avabinosus, amino acids, 75, 76, 
93, 96 
, —— accumulation capacity, 570 
— —, effect, age on glutamate accumulation, 
576 
=~ = osmotic! | factorswaion 
accumulation, 581, 582 
— —, — vitamin B, deficiency on amino acid 
accumulation, 581-588 
— —, glutamate accumulation, 568-577, 581— 
589, 771 
— —, D-glutamic acid, 92 
— —, permeability to glycerol, 582 
— —, — sucrose, 582, 583 
——, rate of amino acid accumulation, 568, 
569 
—  —, retention of accumulated amino acid, 
574, 575 
— —, starvation, effect on pool in, 98 
— —, utilization of y-glutamyl peptides, 60, 
on 
— —, vitamin B, deficiency, effect on, 96, 97 
— casei, amino acids, 77 
— —, distinguishing characteristics, 103, 104 
, peptide uptake, 572 
— delbrueckvi, amino acids, 76 
— plantarum (see also Lactobacillus avabinosus), 
amino acids, 77 
— —, distinguishing characteristics, 103, 104 
Lactone, formation, from hydroxyamino acids, 

amino acid 

> 
Laemophloeus sp., amino acids, 123 
Lamellibranches, octopine, 170 
Lampsilis sp., taurine, absence, 165 
Land gastropods, amino acids, 173 
Laparotomy, effect on pool in liver, 325-327 
Larvae, Drosophila, injection, 147 
Larval and pupal development, insect, pool 
changes in, 125, 126 
Lasiocampa quercus, amino acids, 116 
Lathyrine, occurrence in Lathyrus tingitanus, 
44) 45 
