480 Marine Microbiology 



ments that in 2-methylhexane oxidation by 2-methylhexane- 

 grown Pseudomonos cells both pathways are actually followed. 

 From the ratio of the isolated methyl-substituted hexanoic acids 

 it further follows tliat the Ce-pathway is the predominant one. 

 This conclusion closely agrees with the results of the multiple 

 adaptation experiments, which, e.g., by the slow observed rate of 

 propionic acid oxidation - suggest that the Ci-pathway is of 

 minor importance only. 



A full account of this study, including experimental details, 

 appeared elsewhere (5). 



REFERENCES 



1. Davis, J. B.: Symposium on Petrolemn Microbiology. Bacterial. Rev., 



20:261-264, 1956. 



2. Heringa, J. W., HuYBREGTSE, RosALiNA and Van der Linden, A. C: 



?j-Alkane oxidation by a Pseitdomonas. Formation and j8-oxidation of 

 intermediate fatty acids. Antonie van Leeincenhoek, 27, 1961. 



3. Kennedy, E. P.: Metabolism of lipides. Ann. Rev. Biochem., 26:119-148, 



1957. 



4. Thijsse, G. J. E., and Van der Linden, A. C: n-Alkane oxidation by a 



Pseudomonas. Studies on the intermediate metabolism. Antonie van 

 Leenwenhoek, 24:298-308, 1958. 



5. Thijsse, G. J. E. and Van der Linden, A. C.: Zso-Alkane oxidation by 



a Pseudomonas. Part I. Metabolism of 2-methyl-hexane. Antonia van 

 Leenwenhoek 27:171-179, 1961. 



