X CONTENTS 



Page 



IX. Effects of Deficiency in Human Beings 348 



Richard W. Vilter 



X. Pharmacology 376 



Richard W. Vilter 

 XI. Requirements 



A. Of Animals 380 



Mary Elizabeth Reid 



B. Of Human Beings 388 



Richard W. Vilter 



XII. Future Problems 391 



Mary Elizabeth Reid 



CHAPTER 3. VITAMIN B12 396 



I. Nomenclature and Formulas 397 



Robert S. Harris 



II. Chemistry 397 



Donald E. Wolf and Karl E. Folkers 



III. Industrial Preparation 417 



H. M. Wuest 



IV. Biochemical Systems 421 



Thomas H. Jukes and William. L. Williams 



V. Specificity of Action 443 



Donald E. Wolf and Karl E. Folkers 



VI. Biogenesis 446 



Donald E. Wolf and Karl E. Folkers 



VII. Estimation 448 



Thomas H. Jukes and William L. Williams 



VIII. Standardization of Activity 472 



Thomas H. Jukes and William L. Williams 



IX. Occurrence in Food 476 



Thomas H. Jukes and William L. Williams 



X. Effects of Deficiency 481 



Thomas H. Jukes and William L. Williams 

 XI. Pathology 



A. Chicks 489 



Thomas H. Jukes and William L. Williams 



B. Rats 490 



Thomas H. Jukes and William L. Williams 



C. Human Beings 491 



Frank H. Bethell 



XII. Pharmacology 506 



Frank H. Bethell 

 XIII. Requirements 



A. Of Chicks 507 



Thomas H. Jukes and William L. Williams 



B. Of Rats 513 



Thomas II. Jukes and William L. Williams 



C. Of Pigs 517 



Thomas H. Jukes and William L. Williams 



