656 



SUBJECT INDEX 



p-Aminobenzoic acid, 



in formate utilization, 429-430 



vitamin B12 and, 430 

 D-l-Amino-2-propanol, 



in vitamin B12 , 406-407 

 Amminocobalamin, 468, see also Vitamin 



B12 

 /3 -Amylase, 



ascorbic acid and, 238, 239 

 Anaphylaxis, 



ascorbic acid and, 343-344 

 Androgens, 508 



Anemia, 374, 378, see also Pernicious 

 anemia 



ascorbic acid and, 201 



in biotin deficiency, 603-604 



in folic acid deficiency, 492 



in scurvy, 365-371 



vitamin B12 and, 444, 445-446 

 Anhydro-jS-carotene, 19 

 Anhydrovitamin A, 26, 31-32, 41, 44, 54 



preparation and properties, 48-50 

 Animal protein factor, see also vitamin 

 B12 



identification of, 510-511 

 Animals, 



growth of, 309-310 

 Anthocyanins, 



in ascorbic acid assay, 256-257 

 Antibodies, 



ascorbic acid and, 339-341 

 Anti-egg white injury factor, see Biotin 

 Antimony trichloride, 64 



in vitamin A assay, 30-31, 87-89 

 Anti -pernicious anemia factor, 510-511 

 Antithrombin, 



in scurvy, 293-294 

 Antivitamin A, 26, 55-58 

 Aphanicin, 11 



occurrence of, 101 

 Aphanin, 11 



occurrence of, 101 

 Apocarotenals, 19 

 Apocarotenols, 19 

 Apoerythein, 494 



D-Araboascorbic acid, 192, 196, 198, 205, 

 317 



oxidation of, 228 

 Arginase, 



ascorbic acid and, 238, 239 



Arginine, 



biotin and, 580 

 L-Arginine, 



in separation of biotin isomers, 547 

 Arteries, 



in scurvy, 289 

 Arthritis, 



ascorbic acid and, 380 



differentiation from scurvy, 37 5-37 

 Ascorbic acid, 134 



analogs, 198-202 



assay of, interfering substances in, 

 253-257 



biochemical functions of, 224-242 



biosynthesis of, 211-223 



carbohydrate metabolism and, 241 



catalytic action of, 304-305 



chemistry, 180-208 



citrovorum factor and, 241-242, 432 



as coenzyme, 306 



collagen and, 242 



content of diets, 268 



curative dose of, 378 



deficiency in animals, 269-347 

 in humans, 348-376 



definition of unit, 259 



derivatives, 184-185, 202-208 



distribution of, 261-268, 310-312, 377 



effect on enzymes, 238-239, 331-333 

 on intestinal bacteria, 237 



estimation of, 242-259 



biological methods, 242-244 

 chemical methods, 244-257 

 phj'sical methods, 257-259 



ethers, 205-208 



excretion of, 334-336, 383 



extraction methods, 244-247 



functional aspects of, 302-347 



industrial preparation, 209-211 



in growth of Lactobacilhis, 482 



isolation of, 180-182 



in leucocytes, 291-292 



levels in body fluids, 362-363, 383-384 



metabolism of, 312-313 



mode of action of, 304-306 



nomenclature and formulas, 179-180 



occurrence of, 182-183, 211-212 



oxidation of, 184. 224-228 



pharmacology of, 376-380 



phosphatase and, 239-241 



