SUBJECT INDEX 



057 



properties of, 183-188, 259-261 

 protein metabolism and, 313-315 

 reaction with halogens, 183-184 

 relation to disease, 339-344 

 to growth, 306-310 

 to hormones and stress, 345-347 

 to metabolism, 312-331 

 to minerals, 319-324 

 to other metabolites, 393 

 to other vitamins, 324-331 

 renal thresliold of, 376-377 

 reproduction and, 344-345 

 requirement, 

 factors influencing, 385-388 

 of animals, 380-390 

 of humans, 388-391 

 retention of, 334-336 

 site of formation, 212-213 

 standardization of activity, 259-261 

 synthetic, activity of, 337 

 toxicity of, 321 



tyrosine metabolism and, 236-238 

 ultraviolet absorption of, 185 

 in vitamin Bio assay, 456, 459, 462, 

 463, 466, 467 

 D-Ascorbic acid, 201, 314 

 L-Ascorbic acid, 



synthesis of, 188-198 

 Ascorbic oxidase, 224, 225, 227-228, 230, 



253, 258, 308-309, 322 

 Asparagine, 563 



in vitamin B12 assay, 467 

 Aspartathione, 235 

 Aspartic acid, 

 biotin and, 564, 578, 580 

 deamination of, 582-583, 585 

 in biotin sulfone activity, 563 

 in citrulline synthesis, 581 

 synthesis of, 576-577, 615 

 Aspartic acid deaminase, 



biotin and, 577 

 Astaxanthin, 



conversion to vitamin A, 101 

 Asthma, 378 

 Atelectasis, 111 

 Aureomycin, 418 

 as growth factor, 512, 520 

 in pernicious anemia, 499 

 in thyrotoxicosis, 423 

 Aurochrome, 18 



Auxin, 



relation to ascorbic oxidase, 308 

 Avidin, 581, 599, 603 



affinity for l;iotin analogs, 557-558 



assay of, 594-595 



in biotin deficiency, 586, 589, 591, 

 593, 595 



in determination of biotin require- 

 ment, 617 



in egg white injury, 555-556 



secretion of, 608 



stability of, 556 



tumors and, 610-611 

 Avidin-biotin complex, 



stability of, 556-557 

 Axerophthal, 32 

 Axerophthene, 



preparation and properties, 50 

 Axerophthol, 3, see also Vitamin A 

 Azobenzene, 



as color standard, 88 ' 



B 



Bacteria, 



in dehydroascorbic acid reduction, 

 252-253 

 Bacillus megatherium, 



in vitamin B12 production, 418, 419, 

 487-488 

 Bacteriolysins, 340 

 Barbiturates, 378 

 Benzaldehj'de, 191 

 Benzimidazoles, 



biological activity of, 414 



gljcosides and pentosides of, 415-416 

 Betaine, 484 



vitamin B12 and, 434-438, 441 

 Betanin, 



in ascorbic acic} assay, 257 

 Hile salts, 171, 174 

 Hilirubin, 370, 378 



in scurvy, 365 

 Miocytin, 575 



biological activity <»f, 553 



effect in biotin assay, 594 



isolation of, 553-554 

 Bios n, see Biotin 

 Bios II B, see Biotin 

 Biosterol, 3 



