660 



SUBJECT INDEX 



synthesis, 429 



vitamin Bi2 and, 432-443, 447 

 Chondroitin sulfate, 278, 305-306 



in scurvy, 280-281 



vitamin B12 binding by, 495 

 Chromatography, 



in provitamin A assay, 93-94, 96 



in vitamin A assay, 90-92 

 Chrysomonads, 



in vitamin B12 assay, 460-461 

 Circulatory system, 



ascorbic acid and, 392 



in scurvy, 286-294 

 Citral, 



in vitamin A synthesis, 41-42 

 Citric acid, 



biotin and, 580 

 Citrovorum factor, 497, 500 



synthesis of, 241-242 



vitamin B12 and, 431-432 

 Citrullin, 580 



synthesis in biotin deficiency, 581 

 Clams, 



vitamin B12 in, 465 

 Coast disease, 521 

 Cobalt, 



deficiency, 507, 521 



effect on vitamin B12 production, 420, 

 447, 486 



in vitamin B12 , 400 

 Cold liver oil, 143 

 Coenzyme R, see Biotin 

 Coenzyme I, see Diphosphopyridine 



nucleotide 

 Coenzyme II, see Triphosphopyridine 



nucleotide 

 Collagen, 306 



ascorbic acid and, 242 



formation, 303 



in scurvy, 281, 372 



maintenance of, 276-277 



structure of, 273-274 

 Collagenase, 278 

 Complement, 



ascorbic acid and, 340, 379 



in biotin deficiency, 613 

 Cones, 



pigments in, 59 

 Copper, 323 



effect on urease, 239 



relation to ascorbic acid, 224, 225, 324 



Coprophagy, 



in vitamin nutrition, 588 

 Coproporphyrin, 370 

 Corn, 



in vitamin B12 deficiency, 507 

 Corner sign, 



in scurvy, 360 

 Corpus luteum, 



ascorbic acid in, 312 

 Cortisone, 



effect in scurvy, 347 

 Costochondral junction, 



in scurv}^, 281 

 "Cow manure factor", 508 

 Cozymase, 46, see also Diphosphopyri- 

 dine nucleotide 

 Creatine, 323, 484 

 p-Cresol, 227 

 Crotonic acid, 581 

 Cryptoxanthin, 15, 94, 95 



occurrence of, 101 

 Cucurbita, 



ascorbic oxidase in, 227 

 Cup-plate assays, 



for vitamin B12 , 466-468 

 Cyanide, 



in vitamin B12 , 409 



in vitamin B12 assay, 450-451, 452, 

 457-458, 472, 485 

 Cyanocobalamin, see also Vitamin B12 



in vitamin B12 assay, 452 

 Cyclohexanone, 210 

 Cystathionine, 441 

 Cysteic acid, 



in aspartic acid synthesis, 576 

 Cysteine, 255, 259, 280, 544 



effect on urease, 239 



in ascorbic acid assay, 253 



in dehydroascorbic acid reduction, 233 



in vitamin B12 assay, 459, 462, 463 

 Cystine, 226, 235, 433, 435, 440, 442 



ascorbic acid and, 315 

 Cytochrome, 224, 235 



in ascorbic acid sjaithesis, 217 

 Cytochrome b, 



in dehydroascorbic acid reduction, 236 

 Cytochrome c, 234, 334 

 Cj'tochrome c-cytochrome oxidase, 225 

 Cytochrome oxidase, 225 



ascorbic acid and, 226, 238 



