672 



SUBJECT INDEX 



formate and, 429-430 



in methionine formation, 441-442 

 Sheep, 



vitamin A requirements of, 167-169 

 Shigella parudysentenae Flexner, 340 

 Silicomolj-bdic a(^id, 248 

 Silicone, 451 

 Skin, 



in biotin deficiency, 600-601, 613 



in scurvy, 300-301 



in vitamin A deficiency, 112-113, 149- 

 159 

 Skin factor, see Biotin 

 Sludge, activated, 



as source of vitamin Bij , 420 

 Sodium, 323 



in scurvy, 365 

 Sodium chloride, 



in vitamin Br: assay, 466 

 Sodium methoxide, 191, 192 

 Solvents, 



in provitamin A assay, 94-95 

 Sorbitol, 210 



in ascorbic acid synthesis, 215 

 L-Sorbose, 195 



in ascorbic acid synthesis, 210, 215 

 Soybean protein, 422 



in production of vitamin Bi2 defi- 

 ciency, 490, 507-508, 515, 518 

 "Spectacled ej'es", 



in biotin deficiencj^ 589, 600 

 Spectrophotometry, 



in ascorbic acid assay, 258-259 



of carotenoids, 94-95 

 Sphingomyelin, 286 

 Spleen, 



in scurvy, 298 

 Sprue, 



vitamin B12 and, 445-446 

 Stannous chloride, 252 

 Staphi/lococci, 340, 341 

 Staphi/lococcKS a u reus, 



effect of vitamin B12 analogs on, 488 

 Stearic acid, 



vitamin Br. and, 484 485 

 Steric hindrance, 



in vitamin A isomers, 76 

 Steroids, 



in scurvy, 365, 374 

 Stilbestrol, 



avidin and, 608-609 



Stomach, 298 

 Streptococci, 340 

 Streptomycin, 418, 420 

 Stress, 



effect on ascorbic acid, 377 

 Succinic acid, 582-583 



decarboxylation of, 584, 585 



in dehydroascorbic acid reduction, 236 



metabolism in biotin deficiency, 579 



vitamin B12 and, 484-485 

 Succinic dehydrogenase, 



ascorbic acid and, 238 



biotin and, 576, 584 



in scurvy, 331 

 "Succinoxidase", 



in rhodopsin synthesis, 74 

 Succinylsulfathiazole, 



biotin and, 588, 601, 602 

 Sucrose, 214 



effect on biotin rec[uirement, 565, 588, 

 616 



relation to ascorbic acid synthesis, 221- 

 222 

 Sulfaguanidine, 603 

 p-Sulfamylphenj'lhydrazine, 205 

 Sulfanilamide, 248 



folic acid and, 431 



in vitamin B12 assaj', 466 



vitamin B12 and, 430, 434 

 Sulfhydryl groups, 



in enzyme activity', 69 

 Sulfite, 255 



p-Sulfophenylhydrazine, 248 

 Sulfur, 



in biotin, 533-535 

 Sulfur dioxide, 



in ascorbic acid assay, 254 

 Swine, 



pathologj- of vitamin B12 deficiency, 

 519 



vitamin A requirements of, 167 



vitamin B12 requirement of, 517-520 



Takadiastase, 



in vitamin B12 assay, 471 

 Tannins, 



in ascorbic acid assay, 253 

 Tapeworm, 501-502 



