VII. EFFECTS OF DEFICIENCY 



515 



the true picture may represent a combination of these postulated interac- 

 tions. With these possible interactions in mind, the symptomatolop;y and 

 histopathology of experimental vitamin E deficiency may be more com- 

 prehensible. 



TABLE II 



Listing of References Describing Histopathologic Changes after Vitamin E 



Deficiency in Various Species of Animals 



(The numbers refer to references cited throughout the chapter.) 



b. Histopathologic Lesions in Different Species 



Those structural and functional derangements which appear to be most 

 characteristic of avitaminosis E, whether experimentally induced or oc- 

 curring naturally, are listed in Table II, and under each are cited references 

 to pertinent literature deahng with the types of tissue dysfunction observed 

 in various animal species. It will be noted that lesions of skeletal muscles 

 constitute the most universal finding, and that recorded alterations of 

 other organs and tissues are rather spotty. The absence of recorded lesions 

 in tissues or organs of certain species does not necessarily mean that a 

 need for vitamin E on the part of these structures does not exist; for the 

 most part, it indicates either that the muscular lesions are so pronounced 



