VII. EFFECTS OF DEFICIENTY 



523 



Fig. 2. Skeletal muscle from \'itamin E-deficieiit rat 22 days old, showing "late- 

 lactation" paralysis. Note the strands of fragmented muscle fibers separated by areas 

 of edema and leucocytic infiltration. A few normal fibers can be seen at the periphery 

 of the muscle (left). X 100. (.From Mason. "'i) 



M 



*^* 



fc. X* 



M 





Fig. 3. Skeletal muscle from same rat, at higher magnification, siiowing an area 

 where a group of fibers have undergone necrosis. Portions of two fibers, still po.ssessing 

 cross striations, can be seen at left (S), and several basophilic, spindle-shajjed, multi- 

 nucleate strands representing early stages in regeneration of new fibers at (11). Else- 

 where there is an intermingling of macrophages (M), fibroblasts (F), muscle nuclei 

 with investments of myoplasm (X), endothelial cells and faint outlines of capillaries. 

 A fibroblast in mitosis is seen at lower right. X 440. (From Mason."") 



