596 



NEW AND UNIDENTIFIED GROWTH FACTORS 



TABLE II 



Names for Vitamins and Growth Factors, Now Discarded or Believed 

 Identical with Other Known Compounds 



Factor 



References 



Remarks 



Bs 



Bio and Bii 



Bw; factor W 



B^ 



Li, L2 



Factors R, S (for chick growth) 



Vitamin T (torutiline) 



T factor, for Lactobacillus fer- 



menti 

 Factor U 



Factor V, for Hemophilus 



Factor X 



Factor Y 



Growth factors for guinea pigs: 



GPF-1 



GPF-2 



GPF-3 

 Gizzard erosion factor 



Factors for L. helveticus and iS. 

 lactis: HL 1, 2, 3, and 4 



L. gayoni factor 



Xanthine oxidiise factor 



Williams and Waterman''" 

 Reader'" 



Carter et aL"« 



Centanni'is 



von Euler et al.^^^ 

 Briggs et al.^-" 



Norris and Majnarich'" 

 Hogan et al.-^^ 



Lunde and Kringstad,"^ Elve- 

 hjem et aL'" 



Lunde and Kringstad''^ 

 Nakahara et al.^-'^ 



Schumacher et oZ.-'' 



Goetsch235 



Metcalf et al.^^'' 



Stokstad and Manning-'^ 



Davis'" 



Boas'« 



Chick et aL'" 



Woolley and Sprince'^* 



Almquist and Stokstad, '■'^ 



Bird et oL'" 

 Barton-Wright et aL,'" Colio 



and Babb"» 



Cheldelin and Riggs'^' 



Westerfeld and Richert'^B 



Probably pantothenic acid'" 



Replaceable by mixtures of ar- 

 ginine, glycine, and cystine''^ 



Presumed identical with Be'" or 

 nicotinic acid'" 



Prevented digestive disturbances 

 in pigeons; probably a mixture'" 



Adenylic acid"' 



Probably a mixture of B12 and the 

 folic acid group 



Announced as metabolite of xan- 

 thopterin, but later work failed 

 to confirm earlier results'" 



Antiperosis factor in chicks, re- 

 placeable by manganese"^ and 

 choline'25 



Regarded as identical with bio- 

 tin, "* although properties also 

 resemble pantotlienic acid phos- 

 phates, coenzyme A 



Anti-gray hair factor for rats; prop- 

 erties resemble bound forms of 

 pantothenic acid 



Factors from yeast, liver reportedly 

 related to anthranilic acid, ad- 

 enosine, necessary for normal lac- 

 tation'30. 231 



R = probably related to folic 

 acid,"' S = probably identical 

 with strepogenin"* 



From insects; mixture of folic acid 

 group, B12, desoxyribosides''* 



From tomato juice; may be iden- 

 tical with thiamine"^ 



Probably a mixture containing 

 Be'''" and folic acid activity'^s 



Diphosphopyridine-nucleotide'*' 



Equivalent to biotin"* 



Equivalent to pyridoxine'" 



Identical witli folic acid'''^ 

 Replaceable by cellulose plus am- 

 ino acids'^5 

 Similar to strepogenin'^^ 

 Replaceable by Bis'-" 



Chloroform-soluble fractions from 

 liver; may be related to folic acid 

 group, also lipoic acid 



Partly replaced by nucleotides, '5' 

 plus high levels of folic acid,'*' 

 plus glutamine or asparagine;'^ 

 glucosylglycine active (see text 



122) 



Replaceable by inorganic molyb- 

 date«« 



