648 



SUBJECT INDEX 



Chromotrichia factor, see 30-Aminoben- 

 zoic acid 



Chronaxy, in thiamine deficiency, 466 



Circulatory system, see also Vascular 

 system, p-aminobenzoic acid and, 

 55 



Citric acid, 433 

 tocopherol and, 503 



Citrovorum factor, see also Leucovorin 

 aminopterin and, 158-159 

 chemistry of, 110-121 

 conjugates of, 202 

 function of, 198 

 in animal nutrition, 197-198 

 in leucocytes, 159 

 in monkey anemia, 185-186 

 in reversal of growth inhibition, 202 

 in reversal of pteroylglutamic acid 



analogs, 214-215 

 in scorbutic anemia, 194-195 

 in serine synthesis, 136 

 in sulfonamide reversal, 135 

 location of formyl group, 114-120 

 location of hydrogen, 113-114 

 microbiological activity of, 201-202 

 reduction stage of, 111-114 

 relation to leucovorin, 120-121 

 synthesis of. 111 

 tyrosine and, 192 



Clostridium acetobutylicuvi, in p-amino- 

 benzoic acid estimation, 24-25 



Cobalamin, see Vitamin B12 



Cocaine, 9 



Cocarboxylase, 427, see also Thiamine 

 pyrophosphate 



Codecarboxylase, 234 



Coenzyme A, 578 



achromotrichia and, 39-40 



in pyruvic acid oxidation, 440 



regeneration from acetyl form, 580-581 



Coenzyme I, see Diphosphopyridine 

 nucleotide 



Coenzyme II, see Triphosphopyridine 

 nucleotide 



Coenzyme III, function of, 589 



Colorimctry, in riboflavin estimation, 

 368-369 



Complementary factor, see Vitamin Be 



Conalbumin, 308 



Cortisone, 



p-aminobcnzoic acid and, 58, 62, 83 



myositis and, 560 



pteroylglutamic acid and, 197 



tyrosine and, 192 

 (Jorynehacterium , lipoic acid and, 576 

 Cotransaminase, 234 

 "Crazy chick" disease, 535 

 Creatinine, 268, 272 

 Creatinuria, 511, 559, 560 

 o-Cresyl phosphate, tocopherol and, 



564, 573 

 Crotonobetaine, 584 

 Curare, resemblance to thiamine, 467 

 Cyanide, 437 



as enzjane inhibitor, 14, 15 

 Cyanine dye test, for pyridoxine, 244-245 

 Cyanogen bromide, in pyridoxine esti- 

 mation, 249 

 Cycloform, 8 



Cyclohexanedione-1,2, 444 

 Cyclohexanehexone, 444 

 Cyclopropane, 55 

 Cystathionine, 



cleavage, pjaidoxine and, 239, 269 



synthesis of, 237 

 Cysteic acid, formation of, 589 

 Cysteine, 237 



in enzyme activation, 437 



peptides, 587 

 Cysteine deaminase, 239 

 Cysteine desulfhydrase, in vitamin Be 



deficiency, 269 

 Cysteine-sulfinic acid, oxidation of, 589 

 Cystine, 



hemorrhagic necrosis and, 540 



requirement for, 279 



vitamin Be and, 294-295 

 Cytochrome, 



riboflavin and, 357 



pyruvic dehydrogenase and, 432 

 Cytochrome c reductase, 393 



coenzyme of, 334, 344-345, 346-347 



mechanism of action, 346 



preparation and properties, 345-346, 

 347 

 Cytosine, 125 



D 



Dehydroisoandrosterone acetate, pter- 

 oylglutamic acid and, 197 



5-Dehydroshikimic acid, in aromatic 

 biosynthesis, 18 



