652 



SUBJECT INDEX 



in growth fnctor production, 590-591 



in purine synthesis, 130 



in salicylate detoxification, 82 



in serine synthesis, 136 



in thymine synthesis, 138 



lycomarasmin and, 585 



peptides, utilization of, 586 



pteroylglutamic acid and, 137 



toxicity, 138 



vitamin Be and, 294 

 Glycine oxidase, 



mechanism of action, 354-355 



preparation, 354 



properties, 354 

 Glycylglycine, 9 

 Glycogen, 569 



Glycollate, in pteroylglutamic acid as- 

 say, 201 

 Glyoxal, 444 

 Glyoxylic acid, 444 

 Growth, in vitamin Bq deficiency, 265, 



270, 273, 274 

 Growth factors, unidentified, 594-595 

 Guanidine, formation from folic acid, 95- 



96 

 Guanine, 22, 25, 40 



in growth of microorganisms, 124-125 



in sulfonamide reversal, 69, 77 



synthesis, pteroylglutamic acid and, 

 138-139 

 Guanosine, 318 

 Guinea pig, 



pteroylglutamic acid deficiency in, 189 



tocopherol deficiency in, 518, 520, 525, 

 530 

 Guinea pig antistiffness factor, isolation 

 of, 591 



H 



Haas enzyme, coenzyme of, 343 

 Hamster, 

 p-aminobenzoic acid deficiency in, 42 

 tocopherol deficiency in, 518, 520, 530, 



532, 533, 539, 541 

 vitamin Bo deficiency in, 271 

 vitamin Br, rccjuirement of, 29G 

 Hatchability, tocopherol deficiency and, 



534 

 Heart, in vitamin B,, deficiency, 272, 274- 



275 

 Heart disease, tocopherol and, 565-566 



Heat, pyridoxine and, 295 



Heme, pteroylglutamic acid and, 137 



Hemin, 437 



Hemolysis, tocopherol and, 537, 546-548 



Hemorrhage, in tocopherol deficiency, 



536-537, 550 

 Hepatoflavin, see Riboflavin 

 Hexahydroflavins, 312 

 Hexose monophosphate, 341, 342 

 Hippuric acid, 



formation of, 16 



pteroylglutamic acid and, 137 

 Histaminase, specificity of, 356 

 Histamine, 55-56 



thiamine and, 471 

 Histidine, 



in sulfonamide reversal, 69 



requirement for, 279 

 Homocystine, 239, 268 



in methionine synthesis, 137, 140-142 

 Homogentisic acid, 48 

 Horse, ophthalmia, riboflavin and, 386 

 Human , 



pteroylglutamic acid deficiency in, 

 202-216 



riboflavin deficiency in, 387-391 



riboflavin requirement of, 398-402 



tocopherol deficiency in, 541-562 



vitamin Be deficiency in, 280-290 



vitamin Be requirement of, 298 

 Hydroquinone, 15 



achromotrichia and, 40, 41, 59 

 L-Hydroxy acid oxidase, specificity of, 



353^ 354 

 /3-Hydroxy-7-aminobutyric acid, in 



growth of Tencbrio, 584 

 3-Hydrox3ranthranilic acid, 239 

 p-Hydroxybenzoic acid, 18, 24, 599 



detoxification by, 64 



esters, 65 



formation of, 16 



in p-aminobenzoic acid reversal, 81 

 6-Hydroxychroman, tocopherol and, 487 

 3-Hy(lroxykynurenine, ])yridoxal phos- 

 phate and, 238-239 

 Hydroxjrphenylalanine, 236 

 jo-lTydroxyphenyllactic acid, 191 

 p-Hydroxyphenylpyruvic acid, 191 

 Ilydroxyphenylserine, 236 

 5-Hydroxyuracil, as inhibitor, 150 



