SUBJECT INDEX 



657 



Phytol, in tocopherol sj^nthesis, 496, 498 

 I'hyt}'! bromiilo, in (ocoiiherol synthesis, 



4SS 

 rhytyhhloritlc, in ((jcoplioiol sj'nthesis, 



490 

 Pigment, in tocopherol deficiencj', 516- 



517, 531-532, 538-539 

 Plants, vitamin Be deficiency in, 264 

 Polarography, in vitamin Be estimation, 



244 

 Poliomyelitis, thiamine and, 472 

 Polyneuramin, sec Thiamine 

 PoljTieuritis, 404 

 Polypeptidase, j:;-aminobenzoic acid in, 



13 

 Pontocaine, 8 

 Potatoes, thiamine in, 457 

 Pregnane}', 



thiamine requirement and, 474 



tocopherol level in, 552, 553 



vitamin Be and, 285-286, 287-288, 293 

 Procaine, 8, 55 



p-aminobenzoic acid and, 58 

 Progesterone, tocopherol and, 561 

 Proguanil, see Paludrine 

 Proline, peptides, utilization of, 586 

 Promin, 



p-aminobenzoic acid and, 78 



pteroylglutamic acid and, 174 



pyridoxine and, 291 

 Promizole, pteroylglutamic acid and, 174 

 Propesin, 8 



Propioin, formation of, 443 

 Prothrombin, 55 

 Protein, 



association with pteroylglutamic acid, 

 94-95 



effect on conjugase, 166 



effect on riboflavin requirement, 396- 

 397 



effect on thiamine requirements, 473 



metabolism, vitamin Be and, 267-268, 

 270-271 



pteroylglutamic acid and, 174 



vitamin Be and, 295 

 Protogen, see also Lipoic acid 



in pyruvic acid oxidation, 440 

 Pseudopyridoxine, 231, 277 

 Pteridines, 



substituted, as pteroylglutamic acid 

 analogs, 152-153 



Pteroic acid, 16, 'S,i, 34 

 •activil}' of, 144 

 in sulfonamide reversal, 74 

 synthesis of, 15, 104 

 Pteroylaminoadipic acid, activitj- of, 155 

 Ptcroylaminopimelic acid, activity of, 



155 

 Pteroylaspartic acid, as inhibitor, 154- 



155, 160 

 Pteroyldiglutamic acid, activity of, 142- 



144 

 Pteroylglutamic acid, 28, 42, 583 

 achromotrichia and, 39 

 p-aminobenzoic acid and, 13, 32-34, 



133-136 

 antagonists, 149-161 



resistance to, 160-161 

 biochemical systems of, 124-142 

 chemistry of, 91-121 

 citrovorum factor and, 110 

 cleavage of, 15-16 

 conjugates, 



hydrolysis of, 163-167 

 isolation of, 93-95 

 utilization by fox, 190 

 utilization by Tetrahijmena, 199-200 

 conversion to citrovorum factor, 198 

 degradation of, 95-99 

 derivatives, synthesis of, 108 

 effects of deficiency, 

 in animals, 171-198 

 in human, 202-216 

 in microorganisms, 199-202 

 effect on feathers and pigmentation, 



176 

 endocrine relationships, 195-197 

 estimation of, 



chemical methods, 161-162 

 microbiological methods, 162-168 

 extraction from tissues, 163 

 formation from formylpteroic acid, 



200-201 

 glycine toxicitj- and, 138 

 hydrogenation of, 101-103 

 inabilit}' to replace p-aminobenzoic 



acid, 135-136 

 in p-aminobenzoic acid estimation, 24 

 in choline synthesis, 137-138 

 industrial preparation of, 121-124 

 in foods, 168-171 

 effect of cooking, 204 



