660 



SUBJECT INDEX 



isolation of, 303-305 

 load test, 400-402 

 lyxoflavin and, 588, 589 

 mechanism of action, 357 

 nomenclature and formula, 300-301 

 occurrence in food, 374-377 

 pharmacology of, 391-394 

 precipitation of, 304 

 properties of, 305-309 

 pteroylglutamic acid and, 174 

 purification for assay, 363-364 

 reduction of, 308 

 requirements, 

 of animals, 394-398 

 of human, 398-402 

 solubilizing agents for, 306 

 specificity of, 325-332 

 specificity of action, 358-359 

 stability of, 307-308 

 standardization of, 373-374 

 standards in assay, 364-365 

 synthesis, 



biological, 322-324 

 chemical, 314-322 

 microbiological, 324-325 

 toxicity of, 309, 391-392 

 Riboflavin adenine dinucleotide, 303- 

 304, see also Flavin adenine di- 

 nucleotide 

 Riboflavin monophosphate, 303-304, see 



also Flavin mononucleotide 

 Riboflavin tetraacetate, in growth stimu- 

 lation, 325 

 Ribose, 



in riboflavin synthesis, 314-316 

 preparation of, 318 

 Ribose phosphate, 



formation of, 323-324 

 Ribulose phosphate, formation of, 323- 



324 

 Rice bird, in thiamine assay, 405 

 Rice bran, concentrates of, 409-410 

 Rice germ, concentrates of, 410 

 Rice moth larva test, in pyridoxine es- 

 timation, 253 

 Rickettsial diseases, 12 



p-aminobenzoic acid and, 51, 60-61, 

 79-81 

 Rocky Mountain spotted fever, jo-amino- 

 benzoic acid and, 79 



Rous sarcoma, vitamin deficiency and, 



159-160 

 Ruminants, 



riboflavin deficiency in, 385-386 



vitamin Be and, 298 



Salicylates, 55 



p-aminobenzoic acid and, 61-62, 82 

 Salicyluric acid, 62 



formation of, 82 

 Sarcosine, oxidation of, 354 

 Scleredema, tocopherol and, 550, 569 

 Semicarbazide, pyridoxine and, 291 

 Serine, 135-136, 239, 268 

 in choline synthesis, 137-138 

 in methyl group formation, 198 

 in purine synthesis, 130 

 in sulfonamide reversal, 70, 127-128 

 in thymine synthesis, 138 

 lycomarasmin and, 585 

 requirement for, 279 

 synthesis, pteroylglutamic acid and, 



136-138 

 vitamin Be and, 294 

 Serine deaminase, coenzj^me of, 237-238 

 Serum, 

 tocopherol levels, 

 in disease, 552-554 

 normal, 551-552 

 Serylalanylglutamic acid, strepogenin 



and, 586 

 Serylglycylglutamic acid, strepogenin 



and, 585 

 Shikimic acid, 

 in p-aminobenzoic acid reversal, 81 

 in aromatic biosynthesis, 17-18 

 Size, influence on thiamine requirement, 



473 

 Skin, 

 in riboflavin deficiency, 380-381, 382, 



384, 388-390 

 in vitamin Be deficiency, 265-266 

 Spetrophotometry, in vitamin Be esti- 

 mation, 243-244 

 Sprue, 183 



ceroid and, 556, 557-558 

 pteroylglutamic acid and, 208-209 

 tocopherol and, 553, 554 

 Staphylococcus alb^is, peptide require- 

 ment of, 587 



