SUBJECT INDEX 



GG3 



Tofophorols, 



absorption of, 501-502, 543-544 

 antioxyj^onic action of, 490 



in vitro, 503-504 



in vivo, 502-503 

 biofhoniifal -systems, 501-50G 

 bound forms of, 502 

 catabolism of, 502 

 chemistry, 483-495 

 chromatography of, 497 

 derivatives, 489-491 

 dietary intake of human, 543 

 distillation, 497-498 

 effects of deficiency, 



in animals, 514-541 



in human, 541-562 

 esters, activity of, 490-491 

 estimation, 



biological, 509-512 



chemical, 506-509 

 excretion of, 543-544 

 extraction of, 496-497 

 in adults, 551-562 

 industrial preparation of, 495-501 

 in infants, 545-551 

 isolation of, 484-486 

 isomers, 



differential assay of, 508 



relative activity of, 490 



resolution of, 499 

 mode of administration, 563 

 nomenclature and formulas, 482-483 

 occurrence in foods, 512-514 

 oxidation of, 492-495 

 pharmacology of, 562-570 

 physical properties, 492 

 potency, 



of natural products, 499 



of synthetic products, 499-500 

 production control tests, 500-501 

 requirements, 



of animals, 570-572 



of human, 572-573 

 semiquinone formation, 494 

 sidechain in activity of, 491 

 source materials, 495-496 

 storage of, 502 

 therapeutic use, 564-570 

 tissue levels, 555 

 tissue storage of, 544-545 

 toxicity of, 563 



a-Tocopherol, jjroof of structure, 4S7-488 

 /3-Tocopherol, structure of, 488 

 a-Tocopheroxide, properties of, 495 

 Tocoj)herylhyilro(|uinone, 

 activity of, 493, 530 

 muscular dystrophy and, 559 

 Tocopherylquinone, 

 activity of, 492-493, 530 

 in phisma, 502 

 in tocopherol assay, 506 

 Torulin, see Thiamine 

 TPN, see Triphosphopyridinc nucle<)tide 

 Transaminases, 



coenzyme of, 236-238 

 in vitamin Be activitj', 268, 271 

 Transsulfurization, in vitamin Be de- 

 ficiency, 268-269 

 2,4,5-Triamino-6-hydroxypyrimidine, 

 155 

 in folic acid synthesis, 104-1C6, 122, 124 

 Trichochromogenic factor, see jo-Amino- 



benzoic acid 

 Trimethylhydroquinone, in tocopherol 



synthesis, 488, 496, 498 

 Triphosphopyridinc nucleotide, 314, 341, 

 342, 442 

 oxidation of, 344, 345, 346 

 Trout, 

 pyridoxine requirement of, 298 

 vitamin Be deficiency in, 276 

 Tryparsamide, p-aminobenzoic acid and, 



63 

 Tryptophan, 16, 17-18, 20, 270-271, 281, 

 456 

 effect in pteroylglutaniic acid defi- 



ciency^ 139 

 formation of, 239 

 in sulfonamide reversal, 69 

 in vitamin Be deficiency, 267, 268, 295- 



296 

 metabolism of, 238-239 

 requirement for, 279 

 Tryptophanase, coenzyme of, 238 

 Tryptophan test, in vitamin Be defi- 

 ciency, 28fr-288 

 Tsutsugamuchi disease, /;-aminobcnzoic 



acid and, 79 

 Tumors, 



p-aminoi)enzoic acid and, 61 

 inositol and, 41-42 



