CONTENTS XI 



V. The Attachment Eeaction 212 



A. Keversibility 212 



B. Influence of Temperature 213 



C. Influence of the Medium 214 



D. Trjrptophan Requirement 214 



E. Attachment to Noncellular Surfaces 215 



F. Rate of Attachment 216 



VI. Genetic Control of Attachment Specificity 217 



A. Resistant Cell Mutants 217 



B. Host-Range Mutants of Phages 219 



C. Genetic Control of Tryptophan Requirement 222 



D. Phenotypic Mixing 222 



VII. On the Mechanism of Invasion 223 



A. Alterations of Phage Tail Structure during Invasion 223 



B. Action of Phage Enzyme on the Host Cell Wall 228 



C. Release of Phage DNA 230 



D. Summary of the Steps of Invasion 231 



References 233 



VII. Intracellular Multiplication of Bacterial Viruses by Gunther S. 



Stent 237 



I. Introduction 238 



II. Kinetics of Phage Reproduction 239 



A. One-Step Growth 239 



B. Single Burst 242 



C. Lysis and Lysis Inhibition 243 



D. The Eclipse 246 



III. S}Tithesis of the Bacteriophage Progeny Substance 249 



A Incomplete Bacteriophages 249 



B. The Precursor Pool 254 



C. Maturation 258 



IV. Synthesis of Non precursor Materials 260 



A. Ribonucleic Acid 260 



B. "Early" Protein 261 



V. Fate of the Infecting Phage Particle 263 



A. Functional Differentiation and Injection 263 



B. Transfer of the Parental Nucleic Acid 265 



C. Superinfection Breakdown 269 



VI. Comparative Bacterial Virology 270 



VII. The Vegetative Phage 274 



References 276 



