X. EFFECTS OF DEFICIENCY 



65 



are frequently rough and scarred with a white incrustation, the so-called 

 frosted kidney. 



Fig. 3. Section from t-ortex of kidney of a choline-clefic-ient rat similar to tliose 

 illustrated in Fig. 2. Prominent changes include vascular congestion and tubular 

 degeneration. 



Christensen has described the course of the involution of the thj'mus^ 

 and the renal j^athology'^ which is stuumari/ed as follows (Fig. 3). The 



5 K. Christensen and \V. H. Griffil-li, Endncrinuloim 30, .574 (1<)42). 

 6K. Christensen, Arch. Fulhol. 34, 633 (1942). 



