Fig. 4. Early fibrosis in the liver of a rat in which large amounts of fat had ac- 

 cumulated as a result of inducing a relative deficiency of choline by replacing the 

 drinking water with 15% alcohol (see text). Paraffin section; hematoxylin and 

 eosin stain; X200. (Compare with Fig. 5.) 



Fig. 5. Early fibrosis in the liver of a rat in which large amounts of fat had ac- 

 cumulated as a result of inducing a relative deficiency of choline l)y adding an amount 

 of sucrose to the basal diet, isocaloric with the alcohol consumed by the group of 

 rats illustrated iu Fig. 4 (see text). Technical data as for Fig. 4. 



105 



