386 INOSITOLS 



Starkenstein^^ had early postulated that inositol may be destroyed in the 

 intestines by bacteria, but data to support such a view are not available. 

 The addition of sulfasuxidine to the diet was found by Nielsen and Black^" 

 and Handler-^ to increase the need for inositol, presumably as a result of 

 inhibition of intraintestinal synthesis. 



39 E. Starkenstein, Z. exptl. Path. 5, 378 (1908). 



" E. Nielsen and A. Black, Proc. Soc. Exptl. Biol. Med. 55, 14 (1944). 



