388 



VITAMIN K GROUP 



I. Nomenclature and Formulas 



ROBERT S. HARRIS 



Accepted name: Vitamin K 

 Obsolete names: Antihemorrhagic vitamin 

 Phylloquinones 

 Koagulations vitamin 

 Coagulation vitamin 

 Prothrombin factor 

 Empirical formulas: Vitamin Ki: C31H46O2 

 Vitamin K2: C41H66O2 

 Phthiocol: diHgOa 

 Menadione: C11H8O2 

 Chemical names: Vitamin Ki: 2-methyl-3-phytyl-l,4-naphthoquinone 

 Vitamin K2: 2-methyl-3-difarnesyl-l,4-naphthoqui- 



none 

 Phthiocol: 2-methyl-3-hydroxy-l ,4-naphthoquinone 

 Menadi one : 2-methyl- 1 , 4-naphthoquinone 



Structure : 



H 

 H 



O 



H 11 

 O 



-CH3 



-CH2CH=C— (CH2) 3— CH(CHo) 3— CHCCHa) 3— CHCH3 



1 1 I I 



CH3 CH3 CH3 CH3 



Vitamin Ki 



O 



H 



H 



H 



O 

 O 



-CHs 



-CH2(CH=CCH2CH2)5CH=CCH3 



I I 



CH3 CHs 



Vitamin K2 



O 



H II 

 O 



Phthiocol 



—CHs 

 OH 



H 



-CH. 



« 



H 



O 



Menadione 



