XI. REQUIREMENTS AND FACTORS INFLUENCING THEM G83 



no added "allowance," and are based on the latest figures available. Many 

 of the older values were obtained with diets considered incomplete by to- 

 day's standards or with depleted animals. Values for many animals have 

 not been determined as yet. 



2. Factors Influencing Requirements 



Many factors are known to influence the pantothenic acid requirement 

 of any one species, so actually it is difficult to give one figure as the "re- 

 quirement." A discussion of some of these factors follows: 



a. State of Maturity of the Animal 



As has been seen in the former section, adult animals, in general, recjuire 

 less dietary pantothenic acid than growing animals. Deficiency symptoms 

 are most readily obtained in the very young animal (see section on path- 

 ology and deficiency symptoms). 



■* C. A. Elvehjem, L. M. Henderson, S. Black, and E. Nielsen, /. Biol. Chem. 140, 

 xxxvi (1941). 



* L. M. Henderson, J. M. Mclntire, H. A. Waisman, and C. A. Elvehjem, J. Nutri- 

 tion 23, 47 (1942). 



6 K. Unna and G. V. Richards, J. Nutrition 23, 545 (1942). 



' J. S. D. Bacon and G. N. Jenkins, Biochem. J. 37, 492 (1943). 



» C. A. Slanetz, Am. J. Vet. Research 4, 182 (1943). 



^ C. A. Mills, Arch. Biochem. 1, 73 (1942). 

 1° D. M. Hegsted and T. R. Riggs, /. Nutrition 37, 361 (1949). 



11 H. A. Waisman, R. C. Mills, and C. A. Elvehjem, J. Nutrition 24, 187 (1942). 



12 T. H. Jukes and L. W. McElroy, Poultry Sci. 22, 438 (1943). 

 " J. L. Milligan and G. M. Briggs, Poultr^j Sci. 28, 202 (1949). 



" S. Lepkovsky, F. H. Bird, F. H. Kratzer, and V. S. Asmundson, Poultry Sci. 24, 

 335 (1945). 



15 G. F. Heuser, M. B. Gillis, and L. C. Norris, Kept. 8th World's Poultry Congr. p. 

 114 (1948). 



16 J. C. Bauernfeind, L. C. Norris, and G. F. Heuser, Poultry Sci. 21, 142 (1942). 

 1' A. G. Hogan, Nutrition Abstr. & Revs. 19, 751 (1949-1950). 



18 M. B. Gillis, G. F. Heuser, and L. C. Norris, J. Nutrition 35, 351 (1948). 

 18 M. B. Gillis, G. F. Heuser, and L. C. Norris, /. Nutrition 26, 285 (1943). 



20 F. H. Kratzer and D. Williams, Poultry Sci. 27, 518 (1948). 



21 T. H. Jukes, Poultry Sci. 17, 227 (1938). 



22 W. Trager, J. Exptl. Med. 11, b&l (1943). 



2^ S. C. Stothers, R. R. Johnston, J. A. Hoefer, and R. W. Luecke, J . Animal Sci. 



11, 777 (1952). 

 2^ E. H. Hughes and N. R. Ittner, /. Ani7?ial Sci. 1, 116 (1942). 

 2» A. C. Wiese, W. P. Lehrer, P. R. Moore, 0. F. Pahnish, and W. V. Hartwell, /. 



Animal Sci. 10, 80 (1951). 

 2« A. E. Schaefer, J. M. McKibbin, andC. A. Elvehjem, J. Biol. Chem. 143, 321 (1942). 



27 J. G. Sandza and L. R. Cerecedo, J. Nutrition 21, 609 (1941). 



28 H. P. Morris and S. W. Lippincott, J. Natl. Cancer Inst. 2, 29 (1941). 



