SUBJECT INDEX 



745 



Cholecalciferol, 132, see Vitamin D3 

 Cholestanol, 135, 203 

 A*' '■ 22-Cholestatnene-3-ol, 

 as provitamin D, 142, 145 

 in invertebrates, 155 

 Cholesterilene, 20S sulfonated, 209 

 Cholesterol, 135, 203, 307, 625 

 arteriosclerosis and, 99 

 as source of dehydrocholesterol, 159 

 choline and, 69, 72,97,98 

 dehydrogenation of, 146-148 

 destruction of provitamins in, 207-208 

 effect on 7-dehydrocholesterol, 201- 



202 

 fatty livers and. 20, 82 

 inositol and, 372-373, 384-385 

 in pantothenic acid deficiencj', 652, 



663, 665 

 irradiation of, 138-139 

 occurrence of, 135-136 

 source in animals, 158 

 synthesis of, 622-623 

 vitamin D and, 133, 214-215 

 Cholesterol dibromide, 138-139 

 Cholic acid, effect on gizzard erosion, 



402 

 Choline, 51, 299, 371, 380, 437, 517, 655 

 deficiencj-, 



amino acids and, 76-80 

 biochemistry of, 15-45 

 biogenesis of, 26-28, 43, 49-52, 83 

 chemistry of, 2-14 

 constitution and synthesis, 10-14 

 creatine and, 21-22 

 cyclic sulfate of, 9 

 demethylation of, 40 

 effects of deficiency, 62-123 

 avian species, 93-97 

 dog, 97-101 



general manifestations, 62-63 

 man, 104-123 

 other species, 101-103 

 rat , 63-93 

 effect on fat absorption, 90 

 effect on fatty liver, 19-20, 347 

 estimation of, 52-57 

 biological methods, 57 

 chemical methods, 52-55 

 microbiological methods, 55-57 

 physical methods, 57 

 excretion of, 127 



fate of, 92-93, 126-128 



fatty acids and, 315 



glycerylphosphoric acid esters of, 12 



industrial preparation of, 14 



in growth of bacteria, 49 



in methylation of guanidoacetic acid, 

 30, 31 



inositol and, 370, 385 



in serine formation, 41 



intake of humans, 129 



isolation of, 2-10 



isotopic, 11, 12, 40 



leucocytes and, 90-91 



mechanism of action, 18-45 



niacin toxicity and, 573 



nomenclature, 2 



occurrence of, 58-62 



oxidation of, 25, 43 



pantothenic acid and, 685 



pharmacology of, 123-128 



phospholipids and, 45, 72 



precipitation of, 5 



properties of, 10 



relation to ethanolamine, 40 



requirements 

 of aminals, 128-129 

 of chicks, 94-95 

 of humans, 129-130 



separation from methionine, 55-56 



salts of, 6, 7, 12-14 



separation of different forms, 9 



specificity of action, 45—49 



standardization of activity, 58 



toxicity of, 124-126 



transmethylation and, 19-24, 29, 33 



utilization by guinea pig, 38, 103 



vitamin B12 and, 84-85 



vitamin K and, 88 

 Choline acetylase, 



coenzyme A and, 15-17 



inhibition of, 17 



vitamin K and, 438 

 Choline dehydrogenase, see Choline 



oxidase 

 Cholinesterase, 578 



acetylcholine and, 17 



in fat deficiency, 277 

 Choline oxidase, 67, 82, 127 



in fat deficiency, 278 



in guinea pigs, 103 



inhibitor of, 36 



