746 



SUBJECT INDEX 



in susceptibility to deficiency, 71 



in transmethylation, 26, 28, 33-40 



localization in cell, 35, 36 



vitamin B12 and, 96 

 Cholinepherase, 31 



Choline phosphokinase, substrates of, 19 

 Choline phosphoric acid, 61 

 Chondroitin sulfate, 236-237 

 Chromatography, 



in choline isolation, 9-10 



in isolation of fatty acids, 271-272 



in niacin assay, 535, 536 

 Cinchomeronic acid, niacin formation 



from, 473 

 Cinchophen, 437 



fatty acids and, 317 

 Cirrhosis, 



inositol and, 372 



portal versus non-portal, 114-123 

 Citric acid, 502, 680 



in acetylcholine formation, 16 



synthesis of, 607, 618, 625 

 Citrovorum factor, 



choline oxidase and, 37 



in methyl group transfer, 33 



relation to choline, 83-84 

 Clupanodonic acid, as essential fatty 



acid, 270 

 Coagulation vitamin, see Vitamin K 

 Codehydrase I, see Diphosphopyridine 



nucleotide 

 Codehydrase II, see Triphosphopyridine 



nucleotide 

 Codehydrogenase I, see Diphosphopyri- 

 dine nucleotide 

 Codehydrogenase II, see Triphospho- 

 pyridine nucleotide 

 Cod liver oil, 133 



vitamins D in, 205-206 

 Coenzyme A, 673, 679 



assay of, 599-601, 630 



assay of pantothenic acid in, 610-611 



chemistry of, 603-610 



definition of unit, 633 



distribution of, 614-615, 638 



functions of, 624-625 



in choline acetylation, 15-17 



in fatty acid synthesis, 619 



metabolic functions of, 614-625 



pantothenic acid in, 601 



preparation of, 609-610 



reaction with acid anhydrides, 608 



removal from enzymes, 602 



split products as microbial growth 

 factors, 611-614 



structure of, 608-609 



synthesis of, 604-605 

 Coenzyme I, see Diphosphopyridine 



nucleotide, DPN 

 Coenzyme II, see Triphosphopyridine 



nucleotide, TPN 

 Colchicine, inositol and, 344 

 Cold, effect in choline deficiency, 74 

 Collagen, in cartilage matrix, 236-237 

 Collidine, in industrial niacin produc- 

 tion, 479 

 Colostrum, choline in, 102 

 Conduritol, 338 

 Copper, 



choline and, 76 



deficiency of, 654 

 Coprophagy, vitamin K and, 417, 423 

 Coproporphyrin I, in pantothenic acid 



deficiency, 656 

 Coproporphj^rin III, in pellagra, 562 

 Coprosterol, 203 

 Coramine, see N,N-Dimethylnicotin- 



amide 

 Coreductase, see Diphosphopyridine 



nucleotide 

 Corn, 



as source of inositol, 340-342 



effect on niacin requirement, 584 



pellagra and, 565 



tryptophan and, 524 

 Cortical hormones, 134 

 Corticosterol, in pantothenic acid de- 

 ficiency, 624 

 Cortisone, 



in hj^Doprothrombinemia, 448 



in pantothenic acid deficiency, 652 



liver fat and, 73, 74 

 Cothromboplastin, vitamin K and, 433- 



434 

 Coumalic acid, 478 



Cozymase, see Diphosphopyridine nuc- 

 leotide 

 Creatine, 380, 516 



excretion in leucopenia, 91 



formation of 26, 27, 30-31, 40, 41, 102 



in choline deficiency, 71, 129 



in growth of microorganisms, 50, 55 



in perosis, 93, 97 



methyl groups of, 21-22, 23, 80 



