SUBJECT INDEX 



755 



Lecithinase, 52 



effect on adenosine triphosphatase, 15 



in bone-forming cells, 237 

 Lentine, see Carbaminoylcholine 

 Leuconostoc mesenteroides , in differential 



niacin assay, 540 

 Leucopenia, choline and, 90-91 

 Line test, in vitamin D estimation, 220 

 Linoleic acid, 268, 274, 280, 281 



conjugated, 283 



conversion to arachidonate, 281 



effect in deficiency, 278-280 



effect in double deficiency, 284-285 



isolation of, 270-272 



synthesis of, 272 

 Linolelaidic acid, 283 

 Linolenic acid, 268, 274 



effect in deficiency, 280 



effect in double deficiency, 284-285 



effect on enzymes, 278 



isolation of, 271-272 

 //•ans-Linolenic acid, 282 

 Lipase, in fat deficient diet, 277 

 Lipids, 



in bone-forming cells, 237 



in choline deficiency, 68-76, 98 



inositol in, 334, 366-367 



tissue, in fatty acid deficiency, 307, 

 308-309, 310-311 

 Lipocaic, 371 



choline and, 100-101 



composition of, 86 

 Lipogenesis, 



in choline deficiency, 91 



in pantothenic acid deficiency, 652 

 Lipoprotein, 15 

 Lipositol, 334-335 



composition of, 346 

 Lipoxidase, 280 



in estimation of fatty acids, 289 



specificity of, 312 



substrates of, 278 

 Liver, 



coenzyme A in, 614 



dicoumarol and, 428-429 



in choline deficiency, 63, 67 



in fatty acid deficiency, 299-300 



in prothrombin production, 426-427 



vitamin K and, 401, 437 

 Liver factor 2, see Pantothenic acid 

 Liver filtrate factor, see Pantothenic acid 



Lomiatol, vitamin K and, 397 



Long bones, deformation in rickets, 240 



Lumisterol, 181, 196, 205 



as provitamin D, 144 



formation of, 142, 178 



properties of, 191-192, 202 

 Lymph, in vitamin K absorption, 426 

 Lysine, fatty liver and, 87 



M 



Malic acid, formation of, 499, 500 

 Malic dehydrogenase, 499 



coenzj^me of, 493 



inhibition of, 508 

 "Malic" enzyme, 499 



in carbon dioxide fixation, 504 

 Malonic acid, 



choline oxidase and, 36 



reversal of inhibition by, 366 

 Manganese, 93 

 Meat sugar, see Inositol 

 Mecholyl, see Acetyl-/3-methylcholine 

 Melanin, formation of, 655 

 Menadione, see also Vitamin K, 2- 

 Methyl-1 ,4-naphthoquinone 



inhibitory effects of, 439-440 

 Mercaptoesters, behavior of, 607 

 /9-Mercaptoethylamine, 16 

 Metals, effect on choline oxidase, 36 

 Mercury salts, in choline isolation, 7 

 Metaphysis, in rickets, 245 

 Methanol, in methyl group synthesis, 27, 



84 

 Methionine, 23, 26, 90, 101 



active, 25, 29, 31 



as source of cj^steine, 29 



choline oxidase and, 38 



creatine and, 21-22, 30-31 



effect on fatty liver, 20, 76, 78 



effect on perosis, 94, 97 



ethionine and, SO 



formation, 29, 40, 41 



in epinephrine formation, 32 



in growth of microorganisms, 49, 50, 55 



in inositol deficiency, 368 



in methylation of nicotinamide, 32, 

 516, 517 



in niacin toxicity, 573 



in thiomethyladenosine formation, 51 



in transmethylation, 21-23 



oxidation of, 43 



