756 



SUBJECT INDEX 



pantothenic acid and, 685 



relation to choline 2, 26, 66, 68, 69, 71, 



74, 102, 128, 129 

 requirement of chicks, 94 

 separation from choline, 55-56 

 toxicity of, 92, 95 

 D-Methionine, as methyl donor, 30 

 Methionine sulfoxide, 29, 30 



in transmethjdation, 25 

 Methionine sulfoximine, choline oxidase 



and, 39 

 Methoxinine, choline oxidase and, 39 

 Methyl acceptors, 26-33 

 Methylamine, 

 effect on choline oxidase, 36 

 formation from sarcosine, 42 

 Methylbis-(j3-chloroethyl) amine, effect 



on choline oxidase, 36 

 2-Methyl -3 -difarnesyl-1 ,4 -naphthoqui- 

 none, see vitamin K2 

 3,3'-Methj'lenebis(4-hydroxycoumarin), 



see Dicoumarol 

 Methyl formate, in choline sj'nthesis, 11, 



14 

 Methyl groups, 



oxidation of, 43-44 

 sj^nthesis of, 22 

 3-Methyl-4-hydroxj'coumarin, vitamin 



K and, 399 

 1 -Methyl -2-hydroxynaphthalene, vita- 

 min K and, 397 

 l-Methyl-4-hydroxj'naphthalene, vita- 

 min K and, 397 

 2-Methyl -3-hj^droxynaphthalenes, vita- 

 min K and, 397 

 2-Methyl - 3 - hydroxy -1,4- naphthoqui - 



none, see Vitamin K 

 Methjd iodide, in choline synthesis, 11 

 2-Methyl-l,4-naphthohydroquinone, 

 activity of, 396-397 

 comparative potency of, 410 

 2-Methyl-l ,4-naphthohydroquinone di- 

 phosphate, vitamin K and, 397 

 2-Methyl-l, 4-naphthoquinone, see also 

 Vitamin K 

 activity of, 396 

 choline and, 88 



comparative potencj^ of, 410-411 

 niacin and, 533 



2-Methj'l-l , 4-naphthoquinone diphos- 

 phoric acid ester, 



comparative potencj^ of, 411 

 N'-Methylnicotinamide, 26, 82, 549, 583 



estimation of, 536-537 



excretion of, 515 



folic acid and, 84 



formation of, 23, 32 



in niacin deficiency, 557-558 



isolation of, 456-457 



synthesis of, 477 



toxicity of, 572 



tryptophan and, 524, 530-531 

 N'-Methylnicotinamide-6-pyridone, 



differential assaj^ of, 537 



excretion of, 558 



isolation of, 457 



synthesis of, 478 

 Methjdpantothenic acid, 627 

 Methylphosphate, in creatin formation, 



32 

 2-Meth3d-3-phytyl-l, 4- naphthoquinone, 



see Vitamin K 

 2-Methyl-l-tetralone, vitamin K and, 



397 

 3-Methyl-l-tetralone, vitamin K and, 397 

 Metol, 535 



Metrazole, niacin and, 577 

 Microorganisms, 



choline requirements of, 49-52 



essential fatty acids and, 297-298, 313 



inositol and, 357 



in pantothenic acid assay, 630-633 



niacin synthesis by, 530-531, 533, 583- 

 584 



pantothenic acid deficiency in, 678-680 



vitamin K and, 393, 402, 416-418, 422- 

 424, 439 

 Microsomes, inositol in, 346 

 Milk, 



choline in, 58 



irradiation of, 210-211 



pantothenic acid in, 638 

 Mitochondria, 233 



choline oxidase in, 35 



in creatine formation, 31 



inositol in, 346 

 Modiolus demissus, provitamin D in, 166 

 Monkey, pantothenic acid deficiency in, 



667 

 Monoaminoethanol, formation of, 33 



\ 



