SUBJECT INDEX 



757 



Monoethylcholine, 45 

 Monoiodocalciferol, vitamin D activity 



of, 208 

 Monomethylaniine, formation of, 92 

 p-Monomethylaminoazobenzene, 89 

 Monomethylaminoethanol, 17 



as methyl donor, 28 



effect in choline deficiency, 68, 70, 128 



formation by chick, 40 



in growth of microorganisms, 50-51, 55 



in perosis, 94 



phosphorylation of, 19 

 Monomethylglycine, see also Sarcosine, 



degradation of, 41 

 Monomethyltryptophan, 531 

 Mouse, 



choline deficiency in, 103 



fatty acid deficiency in, 297, 315 



niacin deficiency in, 569 



pantothenic acid deficiency in, 667-668 

 Mucopolj-saccharides, in calcification, 



236 

 Muscarine, resemblance to choline, 123 

 Myosin, 15 

 Mytilitol, 335, 363 



vitamin activity of, 351, 352-353 



N 



(8-Naphthylamine, methylation of, 44 

 Nerves, in pantothenic acid deficiency, 



665-666, 667-668 

 Neurine, 3 



formation of, 11 



in growth of microorganisms, 50, 55 

 Neuromuscular sj-stem, inositol and, 380 

 Neurospora, 



in choline estimation, 55-57 



in inositol assay, 362 



niacin synthesis and, 525-526 

 Niacin, see also Nicotinic acid 



absorption spectrum, 461-462 



acidic character of, 465-466 



antihistaminic effect of, 576-577 



antivitamins in food, 548-550 



as inhibitor, 508 



basic character of, 464-465 



biochemical systems, 480-517 



biosynthesis of, 505, 521-533 



chemistry, 452-478 



constitution of, 473 



crystal structure, 461 



decarboxj'lation of, 513 

 differential assay of, 535-536 

 dissociation constants, 462 

 effects of deficiency, 



in man and animals, 551-565 



in microorganisms, 550-551 

 effect on bilirubin, 576 

 effect on blood sugar, 574-575 

 effect on circulation, 573-574 

 effect on gastric secretion, 575-576 

 estimation, 



biological, 534 



chemical, 534-538 



microbiological, 538-540 

 excretion of, 513, 522, 556-560 

 industrial preparation, 478-479 

 in U. S. diets, 547-548 

 isolation, 452-454 

 isotopic, 476 

 ketosis and, 575 

 load tests of deficiency, 559-560 

 niacinamide synthesis from, 476, 505 

 nomenclature and formulas, 452 

 occurrence of, 541-550 

 pathology, 



in animals, 565-570 



in humans, 570-571 

 pharmacology, 571-578 

 requirements, 



in animals, 578-586 



in human, 586-587 

 separation from niacinamide, 456 

 solubility, 460 



specificity of action, 517-521 

 stability, 460, 545-546 

 standardization of activity, 540 

 synthesis of, 474^78 

 tissue, 514, 554-556 

 toxicity, 



in dogs, 572 



in other species, 572 



in rodents, 571-572 

 urinary metabolites of, 514-516 

 Niacinamide, see also Nicotinamide 

 absorption spectrum, 470-472 

 chemical properties, 472-473 

 crystal structure, 467-470 

 dilTerential assay of, 540 

 dissociation constants, 472 

 in destruction of pyridine nucleotides, 

 507, 508 



